DDX10_MOUSE - dbPTM
DDX10_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID DDX10_MOUSE
UniProt AC Q80Y44
Protein Name Probable ATP-dependent RNA helicase DDX10
Gene Name Ddx10
Organism Mus musculus (Mouse).
Sequence Length 875
Subcellular Localization
Protein Description Putative ATP-dependent RNA helicase..
Protein Sequence MGKTVASLGQGTRPDPVRSFNRWKKKHSHRQHQKKERRKQLKKPEWQVEREGISRLMQNYEKINVNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERINNINILVCTPGRLLQHMDETICFHATNLQMLVLDEADRILDMGFADTMNAIIENLPKKRQTLLFSATQTKSVKDLARLSLKDPEYVWVHEKAKYSTPATLEQNYIICELHQKISVLFSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGISILALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLPSEEQGMVQQLLQKKVPVKEIKINPEKLIDVQKKLESFLAQDQDLKERAQRCFVSYIRSVYLMKDKEVFNVSKLPITEYALSLGLAVAPRIRFLQKLEKQPSTELVKNPVTEAVPPRAPSLPNDEADESPAYVSEKMSVLHKSGERLEETEHRLASGDGDEEQDEETEDEETEDHLGKAREPHTESVVSIEEAQKVKEVSVQFLNRDDDDEDGPDADFLTVKRRDVFGLDLKENEALSKKEPSKSSVKKKLTKVAEAKKVMKRSFKVNKKITFTDEGELVQQWPQIQKCAIKDVEEEDDTGGINLDKAKERLQEEDKFDKEEYRKKIKAKHRERRLKEREARREANKRQAKARDEEEAFLDWSDEDDGGFDPSTLPDPDKHRSSEESESEDTNHKMSDTKKKQETRKRNNTEDDDVRPRSRHGKKAKWETVEPLDTGLSLAEDEELVLHLLKSQN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
4Phosphorylation----MGKTVASLGQG
----CCCCHHHCCCC		18.6429895711
7Phosphorylation-MGKTVASLGQGTRP
-CCCCHHHCCCCCCC		28.7922871156
12PhosphorylationVASLGQGTRPDPVRS
HHHCCCCCCCCHHHH		31.0129895711
89PhosphorylationKGLQEAQYRLVTEIQ
HHHHHHHHHHHHHHH		16.98-
93PhosphorylationEAQYRLVTEIQKQTI
HHHHHHHHHHHHHHH		31.78-
197PhosphorylationNINILVCTPGRLLQH
CCEEEEECCHHHHHH		22.6928576409
249PhosphorylationNLPKKRQTLLFSATQ
HCCHHHCEEEEEECC		29.4820531401
253PhosphorylationKRQTLLFSATQTKSV
HHCEEEEEECCCCCH		30.3120531401
255PhosphorylationQTLLFSATQTKSVKD
CEEEEEECCCCCHHH		35.2620531401
257PhosphorylationLLFSATQTKSVKDLA
EEEEECCCCCHHHHH		22.4120531401
522PhosphorylationQKLEKQPSTELVKNP
HHHHCCCCCHHCCCC		31.8325159016
523PhosphorylationKLEKQPSTELVKNPV
HHHCCCCCHHCCCCC		39.7725159016
540PhosphorylationAVPPRAPSLPNDEAD
CCCCCCCCCCCCCCC		56.3125619855
549PhosphorylationPNDEADESPAYVSEK
CCCCCCCCCCHHHHH		18.5125521595
552PhosphorylationEADESPAYVSEKMSV
CCCCCCCHHHHHHHH		14.1125619855
554PhosphorylationDESPAYVSEKMSVLH
CCCCCHHHHHHHHHC		20.8725619855
556AcetylationSPAYVSEKMSVLHKS
CCCHHHHHHHHHCCC		29.0323806337
576PhosphorylationETEHRLASGDGDEEQ
HHHHHHHCCCCCHHH		41.8522942356
587PhosphorylationDEEQDEETEDEETED
CHHHCCCCCCHHHHH		46.8427087446
592PhosphorylationEETEDEETEDHLGKA
CCCCCHHHHHHHHHC		44.6725619855
606PhosphorylationAREPHTESVVSIEEA
CCCCCCCCEECHHHH		29.0423375375
609PhosphorylationPHTESVVSIEEAQKV
CCCCCEECHHHHHHH		23.3326824392
666PhosphorylationKKEPSKSSVKKKLTK
CCCCCHHHHHHHHHH		41.51-
692PhosphorylationFKVNKKITFTDEGEL
HCCCCCEEECCCCHH		29.3927600695
712MethylationQIQKCAIKDVEEEDD
HHEECEECCCCCCCC		36.88-
729MethylationGINLDKAKERLQEED
CCCHHHHHHHHHHHC		49.46-
737MethylationERLQEEDKFDKEEYR
HHHHHHCCCCHHHHH		59.76-
783PhosphorylationEEAFLDWSDEDDGGF
HHHHCCCCCCCCCCC		30.6821082442
803PhosphorylationPDPDKHRSSEESESE
CCCCCCCCCCCCCCC		41.6525159016
804PhosphorylationDPDKHRSSEESESED
CCCCCCCCCCCCCCC		45.3925159016
807PhosphorylationKHRSSEESESEDTNH
CCCCCCCCCCCCCCC		42.2325159016
809PhosphorylationRSSEESESEDTNHKM
CCCCCCCCCCCCCCC		50.4825159016
812PhosphorylationEESESEDTNHKMSDT
CCCCCCCCCCCCCHH		34.8628066266
831PhosphorylationETRKRNNTEDDDVRP
HHHHHCCCCCCCCCC		44.3226824392
856PhosphorylationETVEPLDTGLSLAED
EECCCCCCCCCHHCC		47.9426745281
859PhosphorylationEPLDTGLSLAEDEEL
CCCCCCCCHHCCHHH		27.2126745281
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of DDX10_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of DDX10_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of DDX10_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of DDX10_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of DDX10_MOUSE

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Large scale localization of protein phosphorylation by use ofelectron capture dissociation mass spectrometry.";
Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.;
Mol. Cell. Proteomics 8:904-912(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-587, AND MASSSPECTROMETRY.

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