DDI1_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DDI1_RAT
• UniProt AC: A0JPP7
• Protein Name: Protein DDI1 homolog 1
• Gene Name: Ddi1
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 408
• Protein Description: Probable aspartic protease..
• Protein Sequence: MLITVYCVRRDLTEVTFSLQVNPDFELSNFRVLCELESGVPAEEAQIVYMEQLLTDDHCSLGSYGLKDGDMVVLLQKDNVGPRPPGRAPNHPRTDFTGSGSAVPGTSSSRHPHPHQHHHHQHQRIPSTQQAHGLASGENMAFAQDLNSPALIRSMLLSNPHDLSLLKERNPALAEALLSGNLETFSQVLVEQQRERAMREQEMFRLYSADPFDQETQARIEEEIRQQNIEENMNIAMEEAPESFGQVAMLYINCKVNGHPLKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGVAKGVGTQRIMGRVHLAQIQIEGDFLQCSFSILEEQPMDILLGLDMLRRHQCSIDLKKNVLVIGTTGSQTHFLPEGELPLCAKLLSGAVQEDSSDKEVAGSIKHPVKGPGRKKH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
136	Phosphorylation	QQAHGLASGENMAFA HHHHCCCCCCCCHHH	52.24	23800682
148	Phosphorylation	AFAQDLNSPALIRSM HHHHCCCCHHHHHHH	20.88	23800682
297	Ubiquitination	RRWAGVAKGVGTQRI HHHHCCCCCCCHHHH	52.28	-
387	Phosphorylation	SGAVQEDSSDKEVAG HCCCCCCCCCCCCCH	39.42	19947656
388	Phosphorylation	GAVQEDSSDKEVAGS CCCCCCCCCCCCCHH	66.09	23800682

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DDI1_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DDI1_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DDI1_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of DDI1_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.