dbPTM

DCNP1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DCNP1_HUMAN
UniProt AC	Q8TF63
Protein Name	Dendritic cell nuclear protein 1 {ECO:0000303\|PubMed:11798177}
Gene Name	DCANP1 {ECO:0000312\|HGNC:HGNC:24459}
Organism	Homo sapiens (Human).
Sequence Length	244
Subcellular Localization	Nucleus . Cytoplasm . Particularly on the periphery. Colocalizes with corticotropin-releasing hormone (CRH) in parvocellular neurons in the paraventricular nucleus.
Protein Description	Binds with and transactivates the corticotropin-releasing hormone (CRH) promoter..
Protein Sequence	MHYGAATHIQNSRSHGLETVPGHQRLERGAGGETPEFPGCHSPAPPENFGNELLPLSAPLQGLSEGLYPPGRNKTLPAGVLREGAVQFLHRGLCNSNLSSEASARPSGTQDELHSSRRKTGQTRREGARKHLVCSFRLYPFTVHTVSPGNSHLALYQVFKAVKLCPSETSFFLSRKSLKSSDPWHPPSLSPNSWNRQAGFRAWSSHLISLSLTCSDSQSRRVSSSQQPPLHSLSSHRRAAHVPE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
100	Phosphorylation	LCNSNLSSEASARPS CCCCCCCHHHHCCCC	40.11	30576142
107	Phosphorylation	SEASARPSGTQDELH HHHHCCCCCCHHHHH	49.25	30576142
115	Phosphorylation	GTQDELHSSRRKTGQ CCHHHHHHHHHHHCC	37.86	30576142
139	Phosphorylation	LVCSFRLYPFTVHTV EEEEEEEEEEEEEEC	7.64	-
142	Phosphorylation	SFRLYPFTVHTVSPG EEEEEEEEEEECCCC	13.58	-
167	Phosphorylation	KAVKLCPSETSFFLS HHHHCCCCCCEEEEC	53.13	25850435
169	Phosphorylation	VKLCPSETSFFLSRK HHCCCCCCEEEECCC	34.86	21955146
170	Phosphorylation	KLCPSETSFFLSRKS HCCCCCCEEEECCCC	15.22	21955146
174	Phosphorylation	SETSFFLSRKSLKSS CCCEEEECCCCCCCC	32.29	21955146

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DCNP1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DCNP1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DCNP1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of DCNP1_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DCNP1_HUMAN

Related Literatures of Post-Translational Modification