| UniProt ID | DCLK3_HUMAN | |
|---|---|---|
| UniProt AC | Q9C098 | |
| Protein Name | Serine/threonine-protein kinase DCLK3 | |
| Gene Name | DCLK3 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 648 | |
| Subcellular Localization | Cytoplasm. Nucleus. | |
| Protein Description | ||
| Protein Sequence | MGKEPLTLKSIQVAVEELYPNKARALTLAQHSRAPSPRLRSRLFSKALKGDHRCGETETPKSCSEVAGCKAAMRHQGKIPEELSLDDRARTQKKWGRGKWEPEPSSKPPREATLEERHARGEKHLGVEIEKTSGEIIRCEKCKRERELQQSLERERLSLGTSELDMGKGPMYDVEKLVRTRSCRRSPEANPASGEEGWKGDSHRSSPRNPTQELRRPSKSMDKKEDRGPEDQESHAQGAAKAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAEKEKKPCMSGGRRMTLRDDQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIETAGKTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 45 | Phosphorylation | RLRSRLFSKALKGDH HHHHHHHHHHHCCCC | 22.93 | 24719451 | |
| 133 | Phosphorylation | GVEIEKTSGEIIRCE CEEEEECCCCEEECH | 45.56 | 24719451 | |
| 158 | Phosphorylation | SLERERLSLGTSELD HHHHHHHHCCCCCCC | 30.86 | 23911959 | |
| 162 | Phosphorylation | ERLSLGTSELDMGKG HHHHCCCCCCCCCCC | 34.07 | 23911959 | |
| 182 | Phosphorylation | EKLVRTRSCRRSPEA HHHHHCCCCCCCCCC | 16.03 | - | |
| 205 | Phosphorylation | WKGDSHRSSPRNPTQ CCCCCCCCCCCCCCH | 38.99 | 17081983 | |
| 206 | Phosphorylation | KGDSHRSSPRNPTQE CCCCCCCCCCCCCHH | 28.03 | 17081983 | |
| 218 | Phosphorylation | TQELRRPSKSMDKKE CHHHCCCCCCCCCCH | 35.23 | 29083192 | |
| 220 | Phosphorylation | ELRRPSKSMDKKEDR HHCCCCCCCCCCHHC | 36.23 | 29083192 | |
| 253 | Phosphorylation | LVEVLPVTEEGLREV HHHHCCCCHHHHHHH | 26.78 | 24719451 | |
| 268 | Phosphorylation | KKDTRPMSRSKHGGW HHCCCCCCCCCCCCC | 35.76 | 24719451 | |
| 382 | Phosphorylation | HRETRQAYAMKIIDK CHHHHHHHHHHHHCH | 10.01 | 29116813 | |
| 390 | Phosphorylation | AMKIIDKSRLKGKED HHHHHCHHHHCCCHH | 38.81 | 20363803 | |
| 408 | Phosphorylation | SEILIIQSLSHPNIV CEEEEEECCCCCCEE | 22.79 | 23532336 | |
| 526 | Phosphorylation | YVAPEILSEKGYGLE CCCHHHHHCCCCCCH | 42.81 | 24719451 | |
| 591 | Phosphorylation | DAAKDLVSRLLVVDP HHHHHHHHHHCCCCC | 25.22 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of DCLK3_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of DCLK3_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of DCLK3_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of DCLK3_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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