DCBD2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DCBD2_MOUSE
• UniProt AC: Q91ZV3
• Protein Name: Discoidin, CUB and LCCL domain-containing protein 2
• Gene Name: Dcbld2
• Organism: Mus musculus (Mouse).
• Sequence Length: 769
• Subcellular Localization: Membrane; Single-pass type I membrane protein.
• Protein Sequence: MASRAPLRAARSPQGPGGPAAPAATGRAALPSAGCCPLPPGRNSSSRPRLLLLLLLLLQDAGGQQGDGCGHTVLGPESGTLTSINYPHTYPNSTVCEWEIRVRTGERIRIKFGDFDIEDSDYCHLNYLKIFNGIGVSRTEIGKYCGLGLQMNQSIESKGSEVTVLFMSGTHAAGRGFLASYSVIDKEDLITCLDTVSNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAGIHAGVVSNVLGGQISIVISKGTPYYESSLANNVTSTVGYLSASLFTFKTSGCYGTLGMESGVIADPQITASSALEWTDHMGQENSWTAEKARLRKPGPPWAAFATDEHQWLQIDLNKEKKITGIVTTGSTMIEHSYYVSAYRVLYSDDGQRWTVYREPGVDQDKIFQGNKDYHKDVRNNFLPPIIARFIRVNPVQWQQKIAMKVELLGCQFTLKGRLPKLTPPPRNGNNLRNTTARPKLGKGRAPKFTQVLQPRSRNELPVQPAETTTTPDIKNTTVTPSVTKDVALAAVLVPVLVMALTTLILILVCAWHWRNRKKKTEGAYDLPHWDRAGWWKGMKQLLPAKSVDHEETPVRYSTSEVSHLSAREVTTVLQADSAEYAQPLVGGIVGTLHQRSTFKPEEGKEAGYADLDPYNSPMQEVYHAYAEPLPVTGPEYATPIVMDMSGHPTASVGLPSTSTFKTAGTQPHALVGTYNTLLSRTDSCSSGQAQYDTPKGGKSAATPEELVYQVPQSTQELSGAGRDEKFDAFKEIL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
92	N-linked_Glycosylation	NYPHTYPNSTVCEWE ECCCCCCCCCEEEEE	39.64	-
152	N-linked_Glycosylation	CGLGLQMNQSIESKG CCCCCCCCCCHHCCC	21.34	-
269	N-linked_Glycosylation	YESSLANNVTSTVGY CHHHHHCCCHHHHHH	32.60	-
469	N-linked_Glycosylation	RNGNNLRNTTARPKL CCCCCCCCCCCCCCC	44.97	-
471	Phosphorylation	GNNLRNTTARPKLGK CCCCCCCCCCCCCCC	24.99	21659604
511	N-linked_Glycosylation	TTTPDIKNTTVTPSV CCCCCCCCCCCCCCC	41.12	-
560	Phosphorylation	KKKTEGAYDLPHWDR CCCCCCCCCCCCHHH	28.95	26032504
582	Phosphorylation	KQLLPAKSVDHEETP HHHCCCCCCCCCCCC	34.58	28973931
593	Phosphorylation	EETPVRYSTSEVSHL CCCCCCCCHHHHCCC	18.20	29514104
601	Phosphorylation	TSEVSHLSAREVTTV HHHHCCCCHHHEEEE	21.61	22807455
616	Phosphorylation	LQADSAEYAQPLVGG EECCCHHHHHHHHHH	15.39	22817900
709	Phosphorylation	QPHALVGTYNTLLSR CCCEEEEHHHHHHHC	13.20	22499769
710	Phosphorylation	PHALVGTYNTLLSRT CCEEEEHHHHHHHCC	10.54	22499769
712	Phosphorylation	ALVGTYNTLLSRTDS EEEEHHHHHHHCCCC	20.75	22499769
715	Phosphorylation	GTYNTLLSRTDSCSS EHHHHHHHCCCCCCC	35.93	22499769
717	Phosphorylation	YNTLLSRTDSCSSGQ HHHHHHCCCCCCCCC	28.96	23984901
719	Phosphorylation	TLLSRTDSCSSGQAQ HHHHCCCCCCCCCCC	18.45	22499769
721	Phosphorylation	LSRTDSCSSGQAQYD HHCCCCCCCCCCCCC	41.26	22499769
722	Phosphorylation	SRTDSCSSGQAQYDT HCCCCCCCCCCCCCC	38.97	23984901
727	Phosphorylation	CSSGQAQYDTPKGGK CCCCCCCCCCCCCCC	25.46	22499769
729	Phosphorylation	SGQAQYDTPKGGKSA CCCCCCCCCCCCCCC	23.20	22499769
735	Phosphorylation	DTPKGGKSAATPEEL CCCCCCCCCCCHHHH	26.81	23984901
738	Phosphorylation	KGGKSAATPEELVYQ CCCCCCCCHHHHEEE	30.83	23984901
744	Phosphorylation	ATPEELVYQVPQSTQ CCHHHHEEECCCCHH	19.20	26032504

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DCBD2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DCBD2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DCBD2_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of DCBD2_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.