dbPTM

DCA13_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DCA13_MOUSE
UniProt AC	Q6PAC3
Protein Name	DDB1- and CUL4-associated factor 13
Gene Name	Dcaf13
Organism	Mus musculus (Mouse).
Sequence Length	445
Subcellular Localization	Nucleus, nucleolus . In the nucleolus, localizes predominantly in the granular component, but also detected in the fibrillar center and dense fibrillar component.
Protein Description	Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity)..
Protein Sequence	MKVKMLSRNPDNYVRETKLDIQRVPRNYDPTLHPFEVPREYVRALNATKLERVFAKPFLASLDGHRDGVNCLAKHPKSLASVLSGACDGEVKIWNLTKRKCIRTIQAHEGFVRGMCTRFCGTSFFTVGDDKTVKQWKMDGPGYGEEEEPLYTVLGKTVYTGIDHHWKDPVFATCGQQVDIWDEQRTSPVCSMNWGFDSISSVKFNPVETFLLGSCASDRNIVLYDMRQATPLKKVILEMRTNTICWNPMEAFNFTAANEDYNLYTFDMRALDTPVMVHMDHVSAVLDVDYSPTGKEFVSASFDKSIRIFPVDKSRSREVYHTKRMQHVMCVKWTSDSKYIMCGSDEMNIRLWKANASEKLGVLTSREKAANDYNQKLKEKFQYHPHVKRIARHRHLPKSIYSQIQEQRVMKEARRRKEMNRRKHSKPGSVPIVSERKKHVVAVVK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
41	Phosphorylation	PFEVPREYVRALNAT CCCCCHHHHHHHCCH	9.12	29514104
49	Acetylation	VRALNATKLERVFAK HHHHCCHHHHHHHCH	46.04	-
157	Phosphorylation	LYTVLGKTVYTGIDH CEECCCEEEECCCCC	19.56	28576409
388	Acetylation	FQYHPHVKRIARHRH HCCCHHHHHHHHHCC	34.74	15628179
423	Acetylation	RKEMNRRKHSKPGSV HHHHHHHHCCCCCCC	49.33	10282039

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DCA13_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DCA13_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DCA13_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of DCA13_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DCA13_MOUSE

Related Literatures of Post-Translational Modification