DBP3_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DBP3_SCHPO
• UniProt AC: Q10202
• Protein Name: ATP-dependent RNA helicase dbp3
• Gene Name: dbp3
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 578
• Subcellular Localization: Nucleus, nucleolus.
• Protein Description: ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity)..
• Protein Sequence: MQFCFRILILYISLSIDNNYLVTTLISLKENVFLHIFTLTFLFKAFLLKMAKRSVEELKRSADEEASVKRKEKKSKHEHKKHKKDKPSADKDRISKKDKKKSKKGKSKTKEESIEINAEEGAKIAQPAIGSANASNHNDEEAYDRYIKKHNISFADPKSSENLLPILQFDELDVSAKLREGLKNYKEPTPIQAATWPYLLAGRDVVGIAETGSGKTVAFGIPALQYLNGLSDNKSVPRVLVVSPTRELAIQTYENLNSLIQGTNLKAVVVYGGAPKSEQARAAKNASVIIGTPGRLLDLINDGSIDCSQVGYLVLDEADRMLDTGFEQDIRNIISHTPDPTRNGSRQTVFFSATWPESVRALAATFLKDPVKITIGSDELAASQNITQIVEILDDPRSKERMLDNLLRKHLSSGGKDDKILIFVLYKKEAARVEGTLARKYNVVGIHGDMSQGARLQALNDFKSGKCPVLVATDVAARGLDIPKVQLVINVTFPLTIEDYVHRIGRTGRANTKGTAITFFTPQDKSHAGELVNVLRQAKQDIPEGLFKFGTAVKPKLNAYGSRVVDVPVKAATKIVFD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
54	Phosphorylation	LLKMAKRSVEELKRS HHHHHHHHHHHHHHH	32.92	29996109
61	Phosphorylation	SVEELKRSADEEASV HHHHHHHHHCHHHHH	38.18	21712547
67	Phosphorylation	RSADEEASVKRKEKK HHHCHHHHHHHHHHH	31.30	21712547
109	Phosphorylation	SKKGKSKTKEESIEI CCCCCCCCHHHHEEE	51.26	25720772
113	Phosphorylation	KSKTKEESIEINAEE CCCCHHHHEEECHHH	26.98	25720772
131	Phosphorylation	IAQPAIGSANASNHN CCCCCCCCCCCCCCC	16.55	21712547
135	Phosphorylation	AIGSANASNHNDEEA CCCCCCCCCCCCHHH	38.13	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DBP3_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DBP3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DBP3_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NC2B_HUMAN	DR1	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.