DBND2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DBND2_HUMAN
• UniProt AC: Q9BQY9
• Protein Name: Dysbindin domain-containing protein 2
• Gene Name: DBNDD2
• Organism: Homo sapiens (Human).
• Sequence Length: 259
• Protein Description: May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro)..
• Protein Sequence: MGAGNFLTALEVPVAALAGAASDRRASCERVSPPPPLPHFRLPPLPRSRLPGPVSRPEPGAPLLGCWLQWGAPSPGPLCLLFRLCSCTCFAPLPAGADMDPNPRAALERQQLRLRERQKFFEDILQPETEFVFPLSHLHLESQRPPIGSISSMEVNVDTLEQVELIDLGDPDAADVFLPCEDPPPTPQSSGMDNHLEELSLPVPTSDRTTSRTSSSSSSDSSTNLHSPNPSDDGADTPLAQSDEEEERGDGGAEPGACS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
142	Phosphorylation	LSHLHLESQRPPIGS HHHHCHHCCCCCCCC	37.54	26074081
149	Phosphorylation	SQRPPIGSISSMEVN CCCCCCCCCEEEEEE	21.73	26074081
151	Phosphorylation	RPPIGSISSMEVNVD CCCCCCCEEEEEECC	25.90	26074081
152	Phosphorylation	PPIGSISSMEVNVDT CCCCCCEEEEEECCC	19.79	26074081
213	Phosphorylation	SDRTTSRTSSSSSSD CCCCCCCCCCCCCCC	32.50	27251275
214	Phosphorylation	DRTTSRTSSSSSSDS CCCCCCCCCCCCCCC	27.41	26126808
215	Phosphorylation	RTTSRTSSSSSSDSS CCCCCCCCCCCCCCC	33.36	27251275
216	Phosphorylation	TTSRTSSSSSSDSST CCCCCCCCCCCCCCC	33.72	26126808
217	Phosphorylation	TSRTSSSSSSDSSTN CCCCCCCCCCCCCCC	35.49	26126808
218	Phosphorylation	SRTSSSSSSDSSTNL CCCCCCCCCCCCCCC	39.86	26126808
219	Phosphorylation	RTSSSSSSDSSTNLH CCCCCCCCCCCCCCC	43.38	30278072
221	Phosphorylation	SSSSSSDSSTNLHSP CCCCCCCCCCCCCCC	40.80	30278072
222	Phosphorylation	SSSSSDSSTNLHSPN CCCCCCCCCCCCCCC	26.72	26126808
223	Phosphorylation	SSSSDSSTNLHSPNP CCCCCCCCCCCCCCC	45.83	27251275
227	Phosphorylation	DSSTNLHSPNPSDDG CCCCCCCCCCCCCCC	29.55	26126808
231	Phosphorylation	NLHSPNPSDDGADTP CCCCCCCCCCCCCCC	55.78	27251275
237	Phosphorylation	PSDDGADTPLAQSDE CCCCCCCCCCCCCHH	21.48	26126808
242	Phosphorylation	ADTPLAQSDEEEERG CCCCCCCCHHHHHCC	41.19	30576142
246	Phosphorylation	LAQSDEEEERGDGGA CCCCHHHHHCCCCCC	51.45	27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DBND2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DBND2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DBND2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KC1D_HUMAN	CSNK1D	physical	16618118
KC1E_HUMAN	CSNK1E	physical	16618118

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.