DALMA_DROME - dbPTM
DALMA_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID DALMA_DROME
UniProt AC Q9VH89
Protein Name Protein dalmatian
Gene Name dmt
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 857
Subcellular Localization Nucleus . Chromosome .
Protein Description Regulator of sister chromatid cohesion in mitosis. Probably involved in development of the central nervous system..
Protein Sequence MVRTRPVPCVPSPDVNTATRRNPGRPKKQSIGADLSTTISKPGRPKKLSIGADLTTIRKPGRPKKLGADLTTIIRKPGRPTKLSNKQSLTALNEPECRIRKCVVKIRRIKVKNGVVSEISRNDAPDVDASTFEPARNSTMYIPSKVQKSTQPQNIKENVAGPETSPCQQRIRSKSPSGPAAEISPKKPPRFFHRDQPLTRTRSSVTRNVFDFLSQSQIEDDSDREDPAADIIQRLVKDGKACVMVRSRKIGKPRAKRTAKKVRPVGNRRKVSTKDNEPEPVKVVPKSIEPRLQKPSRSLSTIFEPEEDYSNDSEHGYVQPIEVPVQVHVEPSTSKQAHEGAYSNLARSVMLNQTQAQNPLPSTDRRRELINMARQLVSTPLNRRAPPVTDVSATTTALSPIAHQSPNAVRTAGGKSPWRVSDDSPLPNTFMFGFNNSQMPSYSSDHVQRRHVYVPDSPVEHAENIPHEESICPPLHEQNHDSNANDSNEENRPPPTISKSMSINDQESEENAENFVHLPNPRRTLQKRTPFKDINILEVVTLPSWKKNVTATVSKEITPTRVAPRPMATSSPAQRSQTRSNLFGFDDDFACEDIPRKSTTPSKGIAPTSMSLNREVTPALANRNQTEVNTFGCNEILPCENIPKEKETNTEERTSSSQNLFGFDEFITESQDSPANFTGLSQNVNLHDKLHRLAELRPRDGELPQVSYTSIRSDCLGESHSKQTDIRYMLCSTMIAPPRPAKRKPAAPTARESMGLFRVDQDEPEQSFADKQPRRTYVKERPQRKRKKRVQILYIESESEDEDEQDSHDKSLDSPEKKRHHVKRPRRDIEHEAKLEQFVTSFNKQCEEVEKFPVIIE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
173PhosphorylationPCQQRIRSKSPSGPA
HHHHHHHHCCCCCCH
34.8022817900
175PhosphorylationQQRIRSKSPSGPAAE
HHHHHHCCCCCCHHH
26.0822817900
177PhosphorylationRIRSKSPSGPAAEIS
HHHHCCCCCCHHHCC
65.5822668510
184PhosphorylationSGPAAEISPKKPPRF
CCCHHHCCCCCCCCC
23.3625749252
222PhosphorylationQSQIEDDSDREDPAA
HHHCCCCCCCCCHHH
51.3823607784
272PhosphorylationVGNRRKVSTKDNEPE
CCCCCCCCCCCCCCC
32.5422817900
273PhosphorylationGNRRKVSTKDNEPEP
CCCCCCCCCCCCCCC
45.4622817900
399PhosphorylationSATTTALSPIAHQSP
CCCCCCCCCCCCCCC
16.2822817900
405PhosphorylationLSPIAHQSPNAVRTA
CCCCCCCCCCCCCCC
15.3922817900
558PhosphorylationATVSKEITPTRVAPR
EEECCCCCCCCCCCC
21.5025749252

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of DALMA_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of DALMA_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of DALMA_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of DALMA_DROME !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of DALMA_DROME

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of Drosophila melanogaster embryos.";
Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.;
J. Proteome Res. 7:1675-1682(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-173; SER-175; SER-184;SER-222 AND SER-405, AND MASS SPECTROMETRY.

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