dbPTM

DAAF4_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DAAF4_RAT
UniProt AC	Q5VJS5
Protein Name	Dynein assembly factor 4, axonemal {ECO:0000312\|RGD:1549760}
Gene Name	Dnaaf4 {ECO:0000312\|RGD:1549760}
Organism	Rattus norvegicus (Rat).
Sequence Length	420
Subcellular Localization	Nucleus. Cytoplasm .
Protein Description	Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. Axonemal dynein assembly factor required for ciliary motility (By similarity)..
Protein Sequence	MPVRVSEFSWQQTPAALFLSLPLRGVCVRDADVFCGESYLKVNFPPFLFEVFLYAPIDDGKSKAKIGNDTILFTLYKKEPVLWESLSMPGVDKEMMQRIREKSILQAQEKAKEATEAKAAAKREDQRYALGEMMKIEEEERKKIEDMKENERKKATRELEAWKECQKKADGQKRVQRKEKPLQGKQAEERGALKPQSLPRKAPPTRLPTRGRNWENIFSEKLKEDRVPAPRSAGSIQISFTPRVFPTALRESQVAEEEEWLHKQAEARRAMSTDLPEFSDLKEEEKNPDWLKDKGNKLFATENYLAAIDAYNLAIRLNRKIPVLYLNRAACHLKLKNLHKAIEDSSKALELLTPPVADNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPANTVVQNDAEKIRNIIQGTTLKSHD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
128	Phosphorylation	AKREDQRYALGEMMK HHHHHHHHHHHHHCH		27097102

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DAAF4_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DAAF4_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DAAF4_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of DAAF4_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DAAF4_RAT

Related Literatures of Post-Translational Modification