D6KL1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: D6KL1_ARATH
• UniProt AC: Q9SUA3
• Protein Name: Serine/threonine-protein kinase D6PKL1
• Gene Name: D6PKL1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 506
• Subcellular Localization: Cell membrane; Peripheral membrane protein. Colocalizes with PIN1 to the basal (lower) membrane of root cells..
• Protein Description: Protein kinase that regulates the auxin transport activity of PIN auxin efflux facilitators by direct phosphorylation. D6PK-mediated PIN phosphorylation promotes auxin transport in the hypocotyl and this is a prerequisite for PHOT1-dependent hypocotyl bending..
• Protein Sequence: MASKYGSGVLPENKKEKGDKETPETSYSSQSVSVNTLADQVSSTLSFAPSSDSKTGGEVKFNEKSDQSGKSNTCRPSTSSDISDESTCSSFSGNNKPHKANDVRWEAIQAVRTKHGVLGLNHFRLLKRLGCGDIGTVHLAELHGTRCFFAMKVMDKGALASRKKLLRAQTEREILQCLDHPFLPTLYSHFETEKFSCLVMEFCPGGDLHTLRQRQPGKRFSEQAAKFYVAEVLLAMEYLHMLGIIYRDLKPENVLVRDDGHVMLSDFDLSLRCTVSPTVVRSTVLASEGQKNSGYCAQPACIQQPSCISAPTTCFSPRYFSSKSKKDKKMKNETGNQVSPLPELVAEPTSARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGKTPFKGSGNRATLFNVVGQPLRFPESPVVSFAARDLIRSLLVKEPQHRLAYKRGATEMKQHPFFEGVNWALVRCASPPEIPKPVDYESAPATPAAATSTSVKSDQSNYLEFDFF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MASKYGSGVLPE ---CCCCCCCCCCCC		22074104
31	Phosphorylation	ETSYSSQSVSVNTLA CCCCCCCCEEHHHHH		28011693
33	Phosphorylation	SYSSQSVSVNTLADQ CCCCCCEEHHHHHHH		28011693
353	Phosphorylation	AEPTSARSMSFVGTH CCCCCCCCCCCCCCC		17317660
355	Phosphorylation	PTSARSMSFVGTHEY CCCCCCCCCCCCCCC		30291188
359	Phosphorylation	RSMSFVGTHEYLAPE CCCCCCCCCCCCCCH		23776212
362	Phosphorylation	SFVGTHEYLAPEIIK CCCCCCCCCCCHHHC		23776212
480	Phosphorylation	PKPVDYESAPATPAA CCCCCCCCCCCCCCC		19880383
489	Phosphorylation	PATPAAATSTSVKSD CCCCCCCCCCCCCCC		19880383
491	Phosphorylation	TPAAATSTSVKSDQS CCCCCCCCCCCCCCC		19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of D6KL1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of D6KL1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of D6KL1_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of D6KL1_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.