D19L3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: D19L3_HUMAN
• UniProt AC: Q6ZPD9
• Protein Name: Probable C-mannosyltransferase DPY19L3
• Gene Name: DPY19L3
• Organism: Homo sapiens (Human).
• Sequence Length: 716
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Description: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins..
• Protein Sequence: MMSIRQRREIRATEVSEDFPAQEENVKLENKLPSGCTSRRLWKILSLTIGGTIALCIGLLTSVYLATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLVQGFHGLIYDNKTESMKTINLLQRMNIYQEVFLSILYRVLPIQKYLEPVYFYIYTLFGLQAIYVTALYITSWLLSGTWLSGLLAAFWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNLQPLSERLTLLAIFISTFLFSLTWQFNQFMMLMQALVLFTLDSLDMLPAVKATWLYGIQITSLLLVCILQFFNSMILGSLLISFNLSVFIARKLQKNLKTGSFLNRLGKLLLHLFMVLCLTLFLNNIIKKILNLKSDEHIFKFLKAKFGLGATRDFDANLYLCEEAFGLLPFNTFGRLSDTLLFYAYIFVLSITVIVAFVVAFHNLSDSTNQQSVGKMEKGTVDLKPETAYNLIHTILFGFLALSTMRMKYLWTSHMCVFASFGLCSPEIWELLLKSVHLYNPKRICIMRYSVPILILLYLCYKFWPGMMDELSELREFYDPDTVELMNWINSNTPRKAVFAGSMQLLAGVKLCTGRTLTNHPHYEDSSLRERTRAVYQIYAKRAPEEVHALLRSFGTDYVILEDSICYERRHRRGCRLRDLLDIANGHMMDGPGENDPDLKPADHPRFCEEIKRNLPPYVAYFTRVFQNKTFHVYKLSRNK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	EIRATEVSEDFPAQE HHHCEECCCCCCCCH	25.80	24173317
61	Phosphorylation	ALCIGLLTSVYLATL HHHHHHHHHHHHHHH	22.61	-
62	Phosphorylation	LCIGLLTSVYLATLH HHHHHHHHHHHHHHC	14.56	-
125	Phosphorylation	NKTESMKTINLLQRM CCCCHHHHHHHHHHC	13.37	-
485	Phosphorylation	LSTMRMKYLWTSHMC HHHHHHHHHHHHHHH	9.72	22210691
488	Phosphorylation	MRMKYLWTSHMCVFA HHHHHHHHHHHHHHH	13.22	22210691
515	Phosphorylation	LLKSVHLYNPKRICI HHHHHHHCCCCCEEE	17.97	22210691
706	Phosphorylation	TRVFQNKTFHVYKLS HHHHHCCCEEEEECC	26.90	26074081
710	Phosphorylation	QNKTFHVYKLSRNK- HCCCEEEEECCCCC-	9.53	26074081
713	Phosphorylation	TFHVYKLSRNK---- CEEEEECCCCC----	29.65	26074081

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of D19L3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of D19L3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of D19L3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of D19L3_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.