D19L1_HUMAN - dbPTM
D19L1_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID D19L1_HUMAN
UniProt AC Q2PZI1
Protein Name Probable C-mannosyltransferase DPY19L1
Gene Name DPY19L1
Organism Homo sapiens (Human).
Sequence Length 675
Subcellular Localization Membrane
Multi-pass membrane protein .
Protein Description Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins..
Protein Sequence MEGRPPPEGRPPPRPRTGRAPRGRRRAVFAAVLHWSHITHLFENDRHFSHLSTLEREMAFRTEMGLYYSYFKTIVEAPSFLNGVWMIMNDKLTEYPLVINTLKRFNLYPEVILASWYRIYTKIMDLIGIQTKICWTVTRGEGLSPIESCEGLGDPACFYVAVIFILNGLMMALFFIYGTYLSGSRLGGLVTVLCFFFNHGECTRVMWTPPLRESFSYPFLVLQMLLVTHILRATKLYRGSLIALCISNVFFMLPWQFAQFVLLTQIASLFAVYVVGYIDICKLRKIIYIHMISLALCFVLMFGNSMLLTSYYASSLVIIWGILAMKPHFLKINVSELSLWVIQGCFWLFGTVILKYLTSKIFGIADDAHIGNLLTSKFFSYKDFDTLLYTCAAEFDFMEKETPLRYTKTLLLPVVLVVFVAIVRKIISDMWGVLAKQQTHVRKHQFDHGELVYHALQLLAYTALGILIMRLKLFLTPHMCVMASLICSRQLFGWLFCKVHPGAIVFAILAAMSIQGSANLQTQWNIVGEFSNLPQEELIEWIKYSTKPDAVFAGAMPTMASVKLSALRPIVNHPHYEDAGLRARTKIVYSMYSRKAAEEVKRELIKLKVNYYILEESWCVRRSKPGCSMPEIWDVEDPANAGKTPLCNLLVKDSKPHFTTVFQNSVYKVLEVVKE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
62PhosphorylationEREMAFRTEMGLYYS
HHHHHHHHHHHHHHH		24.70-
62 (in isoform 2)Ubiquitination-24.7021890473
68PhosphorylationRTEMGLYYSYFKTIV
HHHHHHHHHHHHHHH		11.26-
93PhosphorylationMIMNDKLTEYPLVIN
EHHCCCCCCCCCHHH		38.9330387612
103UbiquitinationPLVINTLKRFNLYPE
CCHHHHHHHCCCCHH		53.5633845483
108PhosphorylationTLKRFNLYPEVILAS
HHHHCCCCHHHHHHH		9.8430387612
115PhosphorylationYPEVILASWYRIYTK
CHHHHHHHHHHHHHH		22.6130387612
121PhosphorylationASWYRIYTKIMDLIG
HHHHHHHHHHHHHHC		16.24-
134S-palmitoylationIGIQTKICWTVTRGE
HCCCCEEEEEECCCC		2.3829575903
176UbiquitinationLMMALFFIYGTYLSG
HHHHHHHHHHHHHCC		2.1323503661
355UbiquitinationLFGTVILKYLTSKIF
HHHHHHHHHHHHHHH		27.3923503661
360UbiquitinationILKYLTSKIFGIADD
HHHHHHHHHHCCCCC		36.5023503661
375PhosphorylationAHIGNLLTSKFFSYK
CCHHHHHHHCCCCHH		32.79-
399UbiquitinationAAEFDFMEKETPLRY
HHHCCCCCCCCCCCC		47.9723503661
402PhosphorylationFDFMEKETPLRYTKT
CCCCCCCCCCCCCHH		38.4024719451
404UbiquitinationFMEKETPLRYTKTLL
CCCCCCCCCCCHHHH		9.5023503661
428UbiquitinationAIVRKIISDMWGVLA
HHHHHHHHHHHHHHH		25.5323503661
433UbiquitinationIISDMWGVLAKQQTH
HHHHHHHHHHHCCCC		2.5123503661
543UbiquitinationEELIEWIKYSTKPDA
HHHHHHHHHCCCCCC		33.9323503661
547UbiquitinationEWIKYSTKPDAVFAG
HHHHHCCCCCCEECC		34.6523503661
558PhosphorylationVFAGAMPTMASVKLS
EECCCCCCCHHHHHH		16.57-
561PhosphorylationGAMPTMASVKLSALR
CCCCCCHHHHHHHCH		14.68-
563UbiquitinationMPTMASVKLSALRPI
CCCCHHHHHHHCHHH		33.94-
576PhosphorylationPIVNHPHYEDAGLRA
HHCCCCCHHHCCHHH		21.69-
587UbiquitinationGLRARTKIVYSMYSR
CHHHHHHHHHHHCCH		3.3023503661
589PhosphorylationRARTKIVYSMYSRKA
HHHHHHHHHHCCHHH		7.38-
590PhosphorylationARTKIVYSMYSRKAA
HHHHHHHHHCCHHHH		10.59-
591UbiquitinationRTKIVYSMYSRKAAE
HHHHHHHHCCHHHHH		1.6123503661
592PhosphorylationTKIVYSMYSRKAAEE
HHHHHHHCCHHHHHH		10.2029759185
593PhosphorylationKIVYSMYSRKAAEEV
HHHHHHCCHHHHHHH		20.75-
611PhosphorylationLIKLKVNYYILEESW
HHHHHHHEEEECCCE		8.55-
616UbiquitinationVNYYILEESWCVRRS
HHEEEECCCEEEECC		46.2023503661
620UbiquitinationILEESWCVRRSKPGC
EECCCEEEECCCCCC		4.6623503661
652UbiquitinationPLCNLLVKDSKPHFT
CCCCEEECCCCCCEE		57.1421890473
652 (in isoform 1)Ubiquitination-57.1421890473
655AcetylationNLLVKDSKPHFTTVF
CEEECCCCCCEEEHH		53.2826051181
665PhosphorylationFTTVFQNSVYKVLEV
EEEHHCCHHHHHHHH		18.9527080861
667PhosphorylationTVFQNSVYKVLEVVK
EHHCCHHHHHHHHHC		8.6627080861
696Ubiquitination----------------------------
----------------------------		21890473
725Ubiquitination---------------------------------------------------------
---------------------------------------------------------		21890473
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of D19L1_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of D19L1_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of D19L1_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of D19L1_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of D19L1_HUMAN

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Related Literatures of Post-Translational Modification

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