dbPTM

CYSKP_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CYSKP_ARATH
UniProt AC	P47999
Protein Name	Cysteine synthase, chloroplastic/chromoplastic
Gene Name	OASB
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	392
Subcellular Localization	Plastid, chloroplast stroma. Plastid, chromoplast.
Protein Description	Acts as a major cysteine synthase..
Protein Sequence	MAATSSSAFLLNPLTSRHRPFKYSPELSSLSLSSRKAAAFDVSSAAFTLKRQSRSDVVCKAVSIKPEAGVEGLNIADNAAQLIGKTPMVYLNNVVKGCVASVAAKLEIMEPCCSVKDRIGYSMITDAEEKGLITPGKSVLVESTSGNTGIGLAFIAASKGYKLILTMPASMSLERRVLLRAFGAELVLTEPAKGMTGAIQKAEEILKKTPNSYMLQQFDNPANPKIHYETTGPEIWEDTRGKIDILVAGIGTGGTITGVGRFIKERKPELKVIGVEPTESAILSGGKPGPHKIQGIGAGFVPKNLDLAIVDEYIAISSEEAIETSKQLALQEGLLVGISSGAAAAAAIQVAKRPENAGKLIAVVFPSFGERYLSTQLFQSIREECEQMQPEL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
61	Acetylation	RSDVVCKAVSIKPEA CCCCEEEEEECCCHH	8.65	22223895
116	N6-(pyridoxal phosphate)lysine	MEPCCSVKDRIGYSM CCCCCCCCHHCCEEE	25.62	-
116	Other	MEPCCSVKDRIGYSM CCCCCCCCHHCCEEE	25.62	-
123	Sulfoxidation	KDRIGYSMITDAEEK CHHCCEEECCCHHHC	2.62	25693801
214	Sulfoxidation	KKTPNSYMLQQFDNP HHCCCCHHCCCCCCC	2.46	25693801
252	Phosphorylation	ILVAGIGTGGTITGV EEEEECCCCCHHHHH	30.44	29654922
367	Phosphorylation	LIAVVFPSFGERYLS EEEEECCCCHHHHHH	34.12	30291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CYSKP_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CYSKP_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CYSKP_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
DPNPH_ARATH	HL	physical	21798944

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CYSKP_ARATH

Related Literatures of Post-Translational Modification