dbPTM

CYSD2_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CYSD2_ARATH
UniProt AC	Q9SXS7
Protein Name	Bifunctional L-3-cyanoalanine synthase/cysteine synthase D2
Gene Name	CYSD2
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	323
Subcellular Localization	Cytoplasm .
Protein Description	Acts as a cysteine synthase. The cysteine synthesis reaction is more efficient than the cyanoalanine synthase activity..
Protein Sequence	MEDRCLIKNDITELIGNTPMVYLNNVVDGCVARIAAKLEMMEPCSSVKDRIAYSMIKDAEDKGLITPGKSTLIEPTAGNTGIGLACMGAARGYKVILVMPSTMSLERRIILRALGAELHLSDQRIGLKGMLEKTEAILSKTPGGYIPQQFENPANPEIHYRTTGPEIWRDSAGKVDILVAGVGTGGTATGVGKFLKEQNKDIKVCVVEPVESPVLSGGQPGPHLIQGIGSGIVPFNLDLTIVDEIIQVAGEEAIETAKLLALKEGLLVGISSGAAAAAALKVAKRPENAGKLIVVVFPSGGERYLSTKLFDSIRYEAENLPIE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
48	N6-(pyridoxal phosphate)lysine	MEPCSSVKDRIAYSM HCCCCCHHHHHHHHH	-
48	Other	MEPCSSVKDRIAYSM HCCCCCHHHHHHHHH	-
55	Sulfoxidation	KDRIAYSMIKDAEDK HHHHHHHHHCCHHHC	25693801
187	Phosphorylation	AGVGTGGTATGVGKF EECCCCHHHHHHHHH	29654922
189	Phosphorylation	VGTGGTATGVGKFLK CCCCHHHHHHHHHHH	29654922
230	Phosphorylation	HLIQGIGSGIVPFNL CEECCCCCCCCCCCC	28011693

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CYSD2_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CYSD2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CYSD2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
DPNPH_ARATH	HL	physical	21798944

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CYSD2_ARATH

Related Literatures of Post-Translational Modification