CYPR_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CYPR_DROME
• UniProt AC: P15425
• Protein Name: Peptidyl-prolyl cis-trans isomerase, rhodopsin-specific isozyme
• Gene Name: ninaA
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 237
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Description: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts on the folding of rhodopsin RH1 and RH2 (but not RH3) and is required for visual transduction..
• Protein Sequence: MKSLLNRIILCSAFLAVASGLSFTVTSRIYMDVKHNKKPVGRITFGLFGKLAPKTVANFRHICLRGINGTSYVGSRFHRVVDRFLVQGGDIVNGDGTGSISIYGDYFPDEDKALAVEHNRPGYLGMANRGPDTNGCQFYVTTVGAKWLDGKHTVFGKVLEGMDTIYAIEDVKTDTDDFPVEPVVISNCGEIPTEQFEFYPDDFNILGWIKAAGLPVTSSFCVLLIFHYFFRQLNMYC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
68	N-linked_Glycosylation	HICLRGINGTSYVGS EEEECCCCCCCCCHH	50.98	1707759

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CYPR_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CYPR_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CYPR_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.