CXCL6_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CXCL6_HUMAN
• UniProt AC: P80162
• Protein Name: C-X-C motif chemokine 6
• Gene Name: CXCL6
• Organism: Homo sapiens (Human).
• Sequence Length: 114
• Subcellular Localization: Secreted.
• Protein Description: Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7)..
• Protein Sequence: MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLRVNPKTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
62	Phosphorylation	TLRVNPKTIGKLQVF EEEECHHHCCEEEEE	35.90	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CXCL6_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CXCL6_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CXCL6_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CXCL6_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.