CX6B1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CX6B1_MOUSE
• UniProt AC: P56391
• Protein Name: Cytochrome c oxidase subunit 6B1
• Gene Name: Cox6b1
• Organism: Mus musculus (Mouse).
• Sequence Length: 86
• Subcellular Localization: Mitochondrion intermembrane space.
• Protein Description: Connects the two COX monomers into the physiological dimeric form..
• Protein Sequence: MAEDIKTKIKNYKTAPFDSRFPNQNQTKNCWQNYLDFHRCEKAMTAKGGDVSVCEWYRRVYKSLCPVSWVSAWDDRIAEGTFPGKI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAEDIKTKI ------CHHHHHHHH	24.14	-
6	Malonylation	--MAEDIKTKIKNYK --CHHHHHHHHHHCC	56.97	26073543
13	Ubiquitination	KTKIKNYKTAPFDSR HHHHHHCCCCCCCCC	47.83	27667366
13	Succinylation	KTKIKNYKTAPFDSR HHHHHHCCCCCCCCC	47.83	23954790
28	Acetylation	FPNQNQTKNCWQNYL CCCCHHCCCCHHHHH	40.10	24062335
30	S-palmitoylation	NQNQTKNCWQNYLDF CCHHCCCCHHHHHHH	4.16	28526873
30	Glutathionylation	NQNQTKNCWQNYLDF CCHHCCCCHHHHHHH	4.16	24333276
30	S-nitrosylation	NQNQTKNCWQNYLDF CCHHCCCCHHHHHHH	4.16	22588120
42	Acetylation	LDFHRCEKAMTAKGG HHHHHCHHHHHCCCC	47.27	23201123
47	Malonylation	CEKAMTAKGGDVSVC CHHHHHCCCCCCHHH	55.02	26320211
47	Succinylation	CEKAMTAKGGDVSVC CHHHHHCCCCCCHHH	55.02	26388266
52	Phosphorylation	TAKGGDVSVCEWYRR HCCCCCCHHHHHHHH	26.28	23737553
54	S-palmitoylation	KGGDVSVCEWYRRVY CCCCCHHHHHHHHHH	2.06	28526873
54	S-nitrosylation	KGGDVSVCEWYRRVY CCCCCHHHHHHHHHH	2.06	22588120
62	Acetylation	EWYRRVYKSLCPVSW HHHHHHHHHHCCCHH	33.81	23576753
65	S-palmitoylation	RRVYKSLCPVSWVSA HHHHHHHCCCHHHCC	3.95	28526873
65	S-nitrosocysteine	RRVYKSLCPVSWVSA HHHHHHHCCCHHHCC	3.95	-
65	S-nitrosylation	RRVYKSLCPVSWVSA HHHHHHHCCCHHHCC	3.95	22588120
65	Glutathionylation	RRVYKSLCPVSWVSA HHHHHHHCCCHHHCC	3.95	24333276
71	Phosphorylation	LCPVSWVSAWDDRIA HCCCHHHCCCCCHHH	19.86	22817900
85	Succinylation	AEGTFPGKI------ HCCCCCCCC------	45.54	23954790
85	Acetylation	AEGTFPGKI------ HCCCCCCCC------	45.54	23864654
85	Ubiquitination	AEGTFPGKI------ HCCCCCCCC------	45.54	27667366

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CX6B1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CX6B1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CX6B1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of CX6B1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.