CUE_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CUE_DROME
• UniProt AC: Q95RU0
• Protein Name: Protein cueball {ECO:0000303|PubMed:8244010}
• Gene Name: cue {ECO:0000312|FlyBase:FBgn0011204}
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 644
• Subcellular Localization: Cell membrane ; Single-pass type I membrane protein .
• Protein Description: Has a role in spermatogenesis and oogenesis..
• Protein Sequence: MIRIRFGMDVLLVLLLATCLLTPAHGTPLEWDFAVTLRTKIQFMDSSWQTIATAAHEFDELSALTFDESEELIYFNDLKHRNGSIFSLKRDLIAANHVAEQTIARTGNESVGGLAYDPLNMNLFWSDTEQRKIFFAPIHGSATPQVLVDLSAEGGRPDGVAVDVCRRKLYWTNSNVTHPTVERINLDGSNRTVIISSNIDMPRGIVVDQLSDRLFWIDDLKGVFFSVESSKLDGSDRQVVLKDKHHEPLNLAVTNDAIYWTDRTTRAVWSHPKVPVIKVTTTSKPDEEDSTDSTDFKDPEPVAEDCPLVRVANLSEEARGIVARTGFYQRLQKDHHCASIVRKVKERVDEQSRKFEIRSLLDQKIKVLEDERCMNDGEYRAATDLCICPTGFKGSRCEIRECHNYCVHGTCQMSELAYPKCYCQPGFKGERCELSVCSGLCLNGGHCRVSKDENEAPSCECPAKFGGARCEQNSTEICSLFCRLLKHEPEMYVPFGCHSICEELAQDNSTNIAIPQYQHLEVCLTPRVWTSSVIIILVVGIVSSLLLVAVIVQGIRRLYKPKRPRIRKTFVVRKQARTNSAGDTPLTNRPLATEQCEITIENCCNMNICETPCFDPKLVEQTLSKSSCKEDKKILIHNMEDDLY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
82	N-linked_Glycosylation	FNDLKHRNGSIFSLK EECCCCCCCCCEEEH	48.56	-
108	N-linked_Glycosylation	QTIARTGNESVGGLA HHHHHHCCCCCCCEE	37.44	-
175	N-linked_Glycosylation	KLYWTNSNVTHPTVE EEEEECCCCCCCCEE	44.79	-
190	N-linked_Glycosylation	RINLDGSNRTVIISS EEECCCCCCEEEEEC	49.53	-
313	N-linked_Glycosylation	CPLVRVANLSEEARG CCEEEEECCCHHHHH	41.04	19349973
473	N-linked_Glycosylation	GGARCEQNSTEICSL CCCCCCCCHHHHHHH	28.71	-
508	N-linked_Glycosylation	CEELAQDNSTNIAIP HHHHHHCCCCCCCCC	38.36	-
644	Phosphorylation	HNMEDDLY------- EECCCCCC-------	24.41	22668510

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CUE_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CUE_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CUE_DROME !!

Protein-Protein Interaction

Oops, there are no PPI records of CUE_DROME !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

N-linked Glycosylation

"Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.";
Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M.,Schiess R., Aebersold R., Watts J.D.;
Nat. Biotechnol. 27:378-386(2009).
Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-313, AND MASSSPECTROMETRY.
PubMed: 19349973