CTR3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CTR3_MOUSE
• UniProt AC: P70423
• Protein Name: Cationic amino acid transporter 3
• Gene Name: Slc7a3
• Organism: Mus musculus (Mouse).
• Sequence Length: 618
• Subcellular Localization: Cell membrane; Multi-pass membrane protein.
• Protein Description: Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner..
• Protein Sequence: MLWQALRRFGQKLVRRRVLELGMGETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLAGLCYAEFGARVPGSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISRTLKGTILLKMPHVLAEYPDFFALALVLLLTGLLVLGASKSALVTKVFTGMNLLVLSFVIISGFIKGELRNWKLTKEDYCLTMSESNGTCSLDSMGSGGFMPFGLEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISMFICFLAYFGVSSALTLMMPYYKLHPESPLPEAFSYVGWEPARYLVAIGSLCALSTSLLGSMFPMPRVMYSMAEDGLLFRVLAKVHSVTHIPIVATLVSGVIAAFMAFLFELTDLVDLMSIGTLLAHSLVSICVLILRYQPDQEMKSVEEEMELQEETLEAEKLTVQALFCPVNSIPTLLSGRVVYVCSSLLAVLLTVLCLVLTWWTTPLRSGDPVWVTVVVLILGLILAISGVIWRQPQNRTPLHFKVPAVPLLPLVSIFVNVYLMMQMTAGTWARFGIWMLIGFAIYFGYGIQHSMKEVKNHQTLPKTRAQTIDLDLTTSCVHSI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Ubiquitination	ALRRFGQKLVRRRVL HHHHHHHHHHHHHHH	49.70	22790023
232	N-linked_Glycosylation	CLTMSESNGTCSLDS EEEEECCCCEEEEEC	45.82	-
437	Ubiquitination	YQPDQEMKSVEEEME HCCCHHHHHHHHHHH	51.07	-
593	Ubiquitination	QHSMKEVKNHQTLPK HHHHHHHHCCCCCCC	50.21	-
600	Ubiquitination	KNHQTLPKTRAQTID HCCCCCCCCCCHHCC	54.47	-
605	Phosphorylation	LPKTRAQTIDLDLTT CCCCCCHHCCCCCCC	18.57	-
611	Phosphorylation	QTIDLDLTTSCVHSI HHCCCCCCCHHHHCC	19.14	22006019
614	S-palmitoylation	DLDLTTSCVHSI--- CCCCCCHHHHCC---	2.76	28680068
617	Phosphorylation	LTTSCVHSI------ CCCHHHHCC------	15.03	22006019

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CTR3_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CTR3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CTR3_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of CTR3_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.