CTHR1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CTHR1_HUMAN
• UniProt AC: Q96CG8
• Protein Name: Collagen triple helix repeat-containing protein 1
• Gene Name: CTHRC1
• Organism: Homo sapiens (Human).
• Sequence Length: 243
• Subcellular Localization: Secreted, extracellular space, extracellular matrix.
• Protein Description: May act as a negative regulator of collagen matrix deposition..
• Protein Sequence: MRPQGPAASPQRLRGLLLLLLLQLPAPSSASEIPKGKQKAQLRQREVVDLYNGMCLQGPAGVPGRDGSPGANGIPGTPGIPGRDGFKGEKGECLRESFEESWTPNYKQCSWSSLNYGIDLGKIAECTFTKMRSNSALRVLFSGSLRLKCRNACCQRWYFTFNGAECSGPLPIEAIIYLDQGSPEMNSTINIHRTSSVEGLCEGIGAGLVDVAIWVGTCSDYPKGDASTGWNSVSRIIIEELPK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
97	Phosphorylation	KGECLRESFEESWTP CCHHHHHHHHHCCCC	31.37	28348404
186	N-linked_Glycosylation	DQGSPEMNSTINIHR CCCCCCCCCEEEEEE	34.05	UniProtKB CARBOHYD
187	Phosphorylation	QGSPEMNSTINIHRT CCCCCCCCEEEEEEC	29.38	29759185
196	Phosphorylation	INIHRTSSVEGLCEG EEEEECCCHHHHHCC	24.47	29759185
228	Phosphorylation	YPKGDASTGWNSVSR CCCCCCCCCCCCEEE	48.19	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CTHR1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CTHR1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CTHR1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CTHR1_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.