| UniProt ID | CSTF1_MOUSE | |
|---|---|---|
| UniProt AC | Q99LC2 | |
| Protein Name | Cleavage stimulation factor subunit 1 | |
| Gene Name | Cstf1 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 431 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (By similarity).. | |
| Protein Sequence | MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNPSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYILLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRSTTD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 67 | Phosphorylation | NDDTAVQYAIGRSDT CCCHHHHHHHCCCCC | 8.12 | 25159016 | |
| 143 | Ubiquitination | DTERMLAKSAMPIEV CHHHHHHHHCCCHHH | 34.48 | - | |
| 204 | Ubiquitination | LKLFDYSKPSAKRAF EEECCCCCHHHHHHH | 36.44 | - | |
| 323 | Phosphorylation | KNSKYILSSGKDSVA CCCCEEECCCCHHHH | 27.73 | - | |
| 324 | Phosphorylation | NSKYILSSGKDSVAK CCCEEECCCCHHHHH | 46.55 | - | |
| 367 | Phosphorylation | VFNHTEDYILLPDER HCCCCCCEEECCCCC | 6.29 | - | |
| 393 | Phosphorylation | AERRNLLSLGHNNIV HHHHHHHHCCCCCEE | 35.16 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CSTF1_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CSTF1_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CSTF1_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of CSTF1_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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