| UniProt ID | CSPG5_RAT | |
|---|---|---|
| UniProt AC | Q9ERQ6 | |
| Protein Name | Chondroitin sulfate proteoglycan 5 | |
| Gene Name | Cspg5 | |
| Organism | Rattus norvegicus (Rat). | |
| Sequence Length | 571 | |
| Subcellular Localization |
Cell membrane Single-pass type I membrane protein . Endoplasmic reticulum membrane Single-pass type I membrane protein . Golgi apparatus membrane Single-pass type I membrane protein . Cell surface . In neurons, localizes to synaptic junctions. |
|
| Protein Description | May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation.. | |
| Protein Sequence | MGRAGGGGPGWGPPPVLLLLGVTLVLTAGAVPAREAGSAIEAEELVRSGLAWESRANDTREEAGLPAAGEDETSWTERGSELAAVGPGVGPEETLEASAAVTGTAWLEADGTGLGGVTAEAGSGDAQTLPATLQAPDEALGSSTMPPAIPEATEASGPPSPTLRDKPSLVPELPKEIPLEVWLNLGGSTPDPQRPEPTFPLQGTLETQPASDIIDIDYFEGLDSEGRGTDMGRFPGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLEEEEEEEEDKDAVGGGDLEDESDLLLPSQKPGVGPGTGQPTSRWHAVPPQHTLGMVPGGSISLRPRPGDPGKDLATSENGTECRVGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGMRCESIITDFQVMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTNKFRTPSELHNDNFSLSTIAEGSHPNVRKLCDTPCVSSPHARALAHCDNIVCQDDPSAPHKIQEALKSRLKEEESFNIQNSMSPKLEGGKGDQDDLEVNCLQNNLT | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 57 | N-linked_Glycosylation | LAWESRANDTREEAG CCEECCCCCCCHHHC | 50.50 | - | |
| 76 | O-linked_Glycosylation | GEDETSWTERGSELA CCCCCCCCCCCCCCE | 18.64 | - | |
| 123 | O-linked_Glycosylation | GVTAEAGSGDAQTLP CEEEECCCCCCCCCC | 40.31 | - | |
| 132 | O-linked_Glycosylation | DAQTLPATLQAPDEA CCCCCCEEECCCHHH | 19.91 | - | |
| 143 | O-linked_Glycosylation | PDEALGSSTMPPAIP CHHHHCCCCCCCCCC | 27.25 | - | |
| 144 | O-linked_Glycosylation | DEALGSSTMPPAIPE HHHHCCCCCCCCCCH | 35.08 | - | |
| 153 | O-linked_Glycosylation | PPAIPEATEASGPPS CCCCCHHHHHCCCCC | 30.35 | - | |
| 156 | O-linked_Glycosylation | IPEATEASGPPSPTL CCHHHHHCCCCCCCC | 45.67 | - | |
| 160 | O-linked_Glycosylation | TEASGPPSPTLRDKP HHHCCCCCCCCCCCC | 33.38 | - | |
| 162 | O-linked_Glycosylation | ASGPPSPTLRDKPSL HCCCCCCCCCCCCCC | 38.47 | - | |
| 198 | O-linked_Glycosylation | DPQRPEPTFPLQGTL CCCCCCCCCCCCCCC | 35.90 | - | |
| 240 | O-linked_Glycosylation | RFPGSPGTSENHPDT CCCCCCCCCCCCCCC | 35.93 | - | |
| 318 | O-linked_Glycosylation | KPGVGPGTGQPTSRW CCCCCCCCCCCCCCC | 35.46 | - | |
| 322 | O-linked_Glycosylation | GPGTGQPTSRWHAVP CCCCCCCCCCCEECC | 24.04 | - | |
| 372 | N-linked_Glycosylation | RVGFVRHNGSCRSVC EEEEEECCCCCCHHH | 33.24 | - | |
| 470 | Phosphorylation | RRTNKFRTPSELHND CCCCCCCCHHHHCCC | 34.01 | 27097102 | |
| 470 (in isoform 2) | Phosphorylation | - | 34.01 | 27097102 | |
| 472 | Phosphorylation | TNKFRTPSELHNDNF CCCCCCHHHHCCCCC | 52.78 | 27097102 | |
| 472 (in isoform 2) | Phosphorylation | - | 52.78 | 27097102 | |
| 480 (in isoform 2) | Phosphorylation | - | 27.88 | 27097102 | |
| 480 | Phosphorylation | ELHNDNFSLSTIAEG HHCCCCCCHHHHCCC | 27.88 | 27097102 | |
| 482 (in isoform 2) | Phosphorylation | - | 19.30 | 27097102 | |
| 482 | Phosphorylation | HNDNFSLSTIAEGSH CCCCCCHHHHCCCCC | 19.30 | 27097102 | |
| 483 (in isoform 2) | Phosphorylation | - | 29.51 | 27097102 | |
| 483 | Phosphorylation | NDNFSLSTIAEGSHP CCCCCHHHHCCCCCC | 29.51 | 27097102 | |
| 488 (in isoform 2) | Phosphorylation | - | 27.55 | 27097102 | |
| 488 | Phosphorylation | LSTIAEGSHPNVRKL HHHHCCCCCCCHHHH | 27.55 | 27097102 | |
| 498 | Phosphorylation | NVRKLCDTPCVSSPH CHHHHCCCCCCCCHH | 20.00 | 27097102 | |
| 502 | Phosphorylation | LCDTPCVSSPHARAL HCCCCCCCCHHHHHH | 44.89 | 27097102 | |
| 503 | Phosphorylation | CDTPCVSSPHARALA CCCCCCCCHHHHHHH | 10.58 | 27097102 | |
| 532 | Ubiquitination | HKIQEALKSRLKEEE HHHHHHHHHHCHHHH | 40.35 | - | |
| 536 | Ubiquitination | EALKSRLKEEESFNI HHHHHHCHHHHCCCC | 63.07 | - | |
| 546 | Phosphorylation | ESFNIQNSMSPKLEG HCCCCCCCCCCCCCC | 12.31 | 25403869 | |
| 548 | Phosphorylation | FNIQNSMSPKLEGGK CCCCCCCCCCCCCCC | 20.78 | 30240740 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CSPG5_RAT !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CSPG5_RAT !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CSPG5_RAT !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of CSPG5_RAT !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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