CSK2B_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CSK2B_MOUSE
• UniProt AC: P67871
• Protein Name: Casein kinase II subunit beta
• Gene Name: Csnk2b
• Organism: Mus musculus (Mouse).
• Sequence Length: 215
• Protein Description: Plays a complex role in regulating the basal catalytic activity of the alpha subunit (By similarity). Participates in Wnt signaling..
• Protein Sequence: MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSSSEEVSW ------CCCHHHHHH	42.44	-
2	Phosphorylation	------MSSSEEVSW ------CCCHHHHHH	42.44	25293948
3	Phosphorylation	-----MSSSEEVSWI -----CCCHHHHHHH	40.23	23649490
4	Phosphorylation	----MSSSEEVSWIS ----CCCHHHHHHHH	30.39	23649490
8	Phosphorylation	MSSSEEVSWISWFCG CCCHHHHHHHHHHHC	23.21	25293948
11	Phosphorylation	SEEVSWISWFCGLRG HHHHHHHHHHHCCCC	14.08	21743459
37	Phosphorylation	IQDKFNLTGLNEQVP HHHHHCCCCHHCCCC	40.50	-
69	Phosphorylation	LEDNPNQSDLIEQAA HCCCCCHHHHHHHHH	40.81	-
108	Phosphorylation	YQQGDFGYCPRVYCE HHCCCCCCCCEEEEC	10.16	22817900
191	Ubiquitination	VPRLYGFKIHPMAYQ CCHHHCCEEECCCHH	35.42	22790023
197	Phosphorylation	FKIHPMAYQLQLQAA CEEECCCHHHHHHHH	11.96	25159016
205	Phosphorylation	QLQLQAASNFKSPVK HHHHHHHHCCCCCCC	45.90	26824392
208	Ubiquitination	LQAASNFKSPVKTIR HHHHHCCCCCCCCCC	59.09	22790023
209	Phosphorylation	QAASNFKSPVKTIR- HHHHCCCCCCCCCC-	30.68	25521595
212	Acetylation	SNFKSPVKTIR---- HCCCCCCCCCC----	41.43	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CSK2B_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CSK2B_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CSK2B_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TC1D3_MOUSE	Tcte3	physical	12849985

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.