CSDC2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CSDC2_MOUSE
• UniProt AC: Q91YQ3
• Protein Name: Cold shock domain-containing protein C2
• Gene Name: Csdc2
• Organism: Mus musculus (Mouse).
• Sequence Length: 154
• Subcellular Localization: Nucleus. Cytoplasm. PIPPin-RNA complexes are located to the nucleus..
• Protein Description: RNA-binding factor which binds specifically to the very 3'-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity)..
• Protein Sequence: MTSESTLPPVVPPLHSPKSPVWPTFPFHREGSRIWERGGGIAPRDLPSPLPTKRTRTYSATARASAGPVFKGVCKQFSRSQGHGFITPENGSEDIFVHVSDIEGEYVPVEGDEVTYKICPIPPKNQKFQAVEVVLTQLAPHTPHETWSGQVVGS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	PVVPPLHSPKSPVWP CCCCCCCCCCCCCCC	41.53	26643407
19	Phosphorylation	PPLHSPKSPVWPTFP CCCCCCCCCCCCCCC	28.24	27180971
32	Phosphorylation	FPFHREGSRIWERGG CCCCCCCCCHHHCCC	18.81	-
37	Methylation	EGSRIWERGGGIAPR CCCCHHHCCCCCCCC	33.78	-
48	Phosphorylation	IAPRDLPSPLPTKRT CCCCCCCCCCCCCCC	46.49	25521595
52	Phosphorylation	DLPSPLPTKRTRTYS CCCCCCCCCCCEEEE	40.62	28066266
59	Phosphorylation	TKRTRTYSATARASA CCCCEEEEEECHHHC	20.66	23737553
65	Phosphorylation	YSATARASAGPVFKG EEEECHHHCCHHHHH	28.36	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CSDC2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CSDC2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CSDC2_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of CSDC2_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.