CRU3_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CRU3_ARATH
• UniProt AC: Q96318
• Protein Name: 12S seed storage protein CRC
• Gene Name: CRC
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 524
• Subcellular Localization: Protein storage vacuole .
• Protein Description: Seed storage protein..
• Protein Sequence: MVKLSNLLVATFGVLLVLNGCLARQSLGVPPQLQNECNLDNLDVLQATETIKSEAGQIEYWDHNHPQLRCVGVSVARYVIEQGGLYLPTFFTSPKISYVVQGTGISGRVVPGCAETFMDSQPMQGQQQGQPWQGRQGQQGQPWEGQGQQGQQGRQGQPWEGQGQQGQQGRQGQQGQPWEGQGQQGQQGFRDMHQKVEHVRRGDVFANTPGSAHWIYNSGEQPLVIIALLDIANYQNQLDRNPRVFHLAGNNQQGGFGGSQQQQEQKNLWSGFDAQVIAQALKIDVQLAQQLQNQQDSRGNIVRVKGPFQVVRPPLRQPYESEEWRHPRSPQGNGLEETICSMRSHENIDDPARADVYKPSLGRVTSVNSYTLPILEYVRLSATRGVLQGNAMVLPKYNMNANEILYCTGGQGRIQVVNDNGQNVLDQQVQKGQLVVIPQGFAYVVQSHGNKFEWISFKTNENAMISTLAGRTSLLRALPLEVISNGFQISPEEARKIKFNTLETTLTRAAGRQQQQLIEEIVEA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
53	Phosphorylation	QATETIKSEAGQIEY HHHHHHHHCCCCCCC	7.28	17313365
78	Phosphorylation	VGVSVARYVIEQGGL EEHHHHHHHHHCCCE	3.16	17313365
97	Phosphorylation	FFTSPKISYVVQGTG EECCCCEEEEEECCC	25.30	17313365
103	Phosphorylation	ISYVVQGTGISGRVV EEEEEECCCCCCEEC	2.03	27288362
106	Phosphorylation	VVQGTGISGRVVPGC EEECCCCCCEECCCH	2.31	27288362
116	Phosphorylation	VVPGCAETFMDSQPM ECCCHHHHHHCCCCC	9.29	17313365
120	Phosphorylation	CAETFMDSQPMQGQQ HHHHHHCCCCCCCCC	36.41	27288362
259	Phosphorylation	QQGGFGGSQQQQEQK CCCCCCCCHHHHHHH	59.34	17313365
366	Phosphorylation	PSLGRVTSVNSYTLP CCCCCEEEECCCCCC	27.88	17313365
370	Phosphorylation	RVTSVNSYTLPILEY CEEEECCCCCCHHHH	4.46	24894044
406	Phosphorylation	MNANEILYCTGGQGR CCCCEEEEEECCCCC	36.19	24243849
459	Phosphorylation	FEWISFKTNENAMIS EEEEEEECCCCHHHH		17313365
473	Phosphorylation	STLAGRTSLLRALPL HHHCCCHHHHHHCCH		29797451
484	Phosphorylation	ALPLEVISNGFQISP HCCHHHHCCCCCCCH		17313365
501	Phosphorylation	ARKIKFNTLETTLTR HHCCCCCCHHHHHHH		19423640
504	Phosphorylation	IKFNTLETTLTRAAG CCCCCHHHHHHHHHH		27288362
505	Phosphorylation	KFNTLETTLTRAAGR CCCCHHHHHHHHHHH		27288362
507	Phosphorylation	NTLETTLTRAAGRQQ CCHHHHHHHHHHHHH		27288362

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CRU3_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CRU3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CRU3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UBQ3_ARATH	UBQ3	physical	25907570

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphorylation of the 12 S globulin cruciferin in wild-type andabi1-1 mutant Arabidopsis thaliana (thale cress) seeds.";
Wan L., Ross A.R., Yang J., Hegedus D.D., Kermode A.R.;
Biochem. J. 404:247-256(2007).
Cited for: IDENTIFICATION BY MASS SPECTROMETRY, AND PHOSPHORYLATION AT THR-109;TYR-299; SER-367; THR-395; THR-420 AND SER-436.
PubMed: 17313365