CRU1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CRU1_ARATH
• UniProt AC: P15455
• Protein Name: 12S seed storage protein CRA1
• Gene Name: CRA1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 472
• Subcellular Localization: Protein storage vacuole .
• Protein Description: Seed storage protein..
• Protein Sequence: MARVSSLLSFCLTLLILFHGYAAQQGQQGQQFPNECQLDQLNALEPSHVLKSEAGRIEVWDHHAPQLRCSGVSFARYIIESKGLYLPSFFNTAKLSFVAKGRGLMGKVIPGCAETFQDSSEFQPRFEGQGQSQRFRDMHQKVEHIRSGDTIATTPGVAQWFYNDGQEPLVIVSVFDLASHQNQLDRNPRPFYLAGNNPQGQVWLQGREQQPQKNIFNGFGPEVIAQALKIDLQTAQQLQNQDDNRGNIVRVQGPFGVIRPPLRGQRPQEEEEEEGRHGRHGNGLEETICSARCTDNLDDPSRADVYKPQLGYISTLNSYDLPILRFIRLSALRGSIRQNAMVLPQWNANANAILYVTDGEAQIQIVNDNGNRVFDGQVSQGQLIAVPQGFSVVKRATSNRFQWVEFKTNANAQINTLAGRTSVLRGLPLEVITNGFQISPEEARRVKFNTLETTLTHSSGPASYGRPRVAAA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
115	Phosphorylation	VIPGCAETFQDSSEF CCCCHHHHHCCCCCC	46.81	22440515
234	Phosphorylation	ALKIDLQTAQQLQNQ HHHHCHHHHHHHHCC	10.38	27288362
312	Phosphorylation	VYKPQLGYISTLNSY CCCCCCEEEECCCCC	28.41	17313365
314	Phosphorylation	KPQLGYISTLNSYDL CCCCEEEECCCCCCC	29.61	17313365
408	Phosphorylation	FQWVEFKTNANAQIN EEEEEEECCCCHHHH	30.69	-
433	Phosphorylation	GLPLEVITNGFQISP CCCEEEECCCCCCCH	37.81	29797451
464	Phosphorylation	HSSGPASYGRPRVAA CCCCCHHHCCCCCCC	3.61	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CRU1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CRU1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CRU1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UBQ3_ARATH	UBQ3	physical	25907570

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphorylation of the 12 S globulin cruciferin in wild-type andabi1-1 mutant Arabidopsis thaliana (thale cress) seeds.";
Wan L., Ross A.R., Yang J., Hegedus D.D., Kermode A.R.;
Biochem. J. 404:247-256(2007).
Cited for: IDENTIFICATION BY MASS SPECTROMETRY, AND PHOSPHORYLATION AT SER-53;TYR-78; SER-97; THR-116; SER-259; SER-366; THR-459; SER-484 ANDTHR-501.
PubMed: 17313365