| UniProt ID | CRLD2_HUMAN | |
|---|---|---|
| UniProt AC | Q9H0B8 | |
| Protein Name | Cysteine-rich secretory protein LCCL domain-containing 2 | |
| Gene Name | CRISPLD2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 497 | |
| Subcellular Localization | Secreted. | |
| Protein Description | Promotes matrix assembly.. | |
| Protein Sequence | MSCVLGGVIPLGLLFLVCGSQGYLLPNVTLLEELLSKYQHNESHSRVRRAIPREDKEEILMLHNKLRGQVQPQASNMEYMTWDDELEKSAAAWASQCIWEHGPTSLLVSIGQNLGAHWGRYRSPGFHVQSWYDEVKDYTYPYPSECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTCRKMTVWGEVWENAVYFVCNYSPKGNWIGEAPYKNGRPCSECPPSYGGSCRNNLCYREETYTPKPETDEMNEVETAPIPEENHVWLQPRVMRPTKPKKTSAVNYMTQVVRCDTKMKDRCKGSTCNRYQCPAGCLNHKAKIFGTLFYESSSSICRAAIHYGILDDKGGLVDITRNGKVPFFVKSERHGVQSLSKYKPSSSFMVSKVKVQDLDCYTTVAQLCPFEKPATHCPRIHCPAHCKDEPSYWAPVFGTNIYADTSSICKTAVHAGVISNESGGDVDVMPVDKKKTYVGSLRNGVQSESLGTPRDGKAFRIFAVRQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 27 | N-linked_Glycosylation | SQGYLLPNVTLLEEL CCCCCCCCHHHHHHH | 39.10 | UniProtKB CARBOHYD | |
| 241 | O-linked_Glycosylation | CYREETYTPKPETDE EECCCCCCCCCCCCC | 32.05 | OGP | |
| 254 | O-linked_Glycosylation | DEMNEVETAPIPEEN CCCCCCCCCCCCCCC | 42.80 | OGP | |
| 283 | Phosphorylation | KKTSAVNYMTQVVRC CCCCHHHHHHEEEEC | 8.57 | 22817900 | |
| 285 | Phosphorylation | TSAVNYMTQVVRCDT CCHHHHHHEEEECCC | 14.09 | 22817900 | |
| 292 | Phosphorylation | TQVVRCDTKMKDRCK HEEEECCCCCCCCCC | 36.34 | 22817900 | |
| 322 | Phosphorylation | HKAKIFGTLFYESSS HCCEEEEEEEHHCCH | 11.71 | - | |
| 369 | Phosphorylation | SERHGVQSLSKYKPS CCCCCCCCHHHCCCC | 32.00 | 19664995 | |
| 376 | Phosphorylation | SLSKYKPSSSFMVSK CHHHCCCCCCEEEEE | 34.17 | - | |
| 382 | Phosphorylation | PSSSFMVSKVKVQDL CCCCEEEEEEEECCC | 21.68 | - | |
| 467 | Phosphorylation | MPVDKKKTYVGSLRN EECCCCCEEEECCCC | 32.11 | 28152594 | |
| 468 | Phosphorylation | PVDKKKTYVGSLRNG ECCCCCEEEECCCCC | 16.22 | 28152594 | |
| 471 | Phosphorylation | KKKTYVGSLRNGVQS CCCEEEECCCCCCCC | 17.70 | 28152594 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CRLD2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CRLD2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CRLD2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| HS90B_HUMAN | HSP90AB1 | physical | 26186194 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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