CRK6_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CRK6_ARATH
• UniProt AC: Q9C5S9
• Protein Name: Cysteine-rich receptor-like protein kinase 6
• Gene Name: CRK6
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 674
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MSSLISFNFLFLFSFLTSSFTASAQDPFYLNHYCPNTTTYSSNSTYSTNLRTLLSSLSSRNASYSTGFQNATAGKAPDRVTGLFLCRGDVSPEVCRNCVAFSVNQTLNLCPKVREAVFYYEQCILRYSHKNILSTAITNEGEFILSNTNTISPNQKQIDGFTSFVSSTMSEAAGKAANSSRKLYTVNTELTAYQNLYGLLQCTPDLTRADCLSCLQSSINGMALSRIGARLYWPSCTARYELYPFYNESAIETPPLPPPPPPPPPRESLVSTPPISSSSLPGKSGNSTVLVVAVVVLAVLLFIALVGYCFLAKKKKKTFDTASASEVGDDMATADSLQLDYRTIQTATNDFAESNKIGRGGFGEVYKGTFSNGKEVAVKRLSKNSRQGEAEFKTEVVVVAKLQHRNLVRLLGFSLQGEERILVYEYMPNKSLDCLLFDPTKQIQLDWMQRYNIIGGIARGILYLHQDSRLTIIHRDLKASNILLDADINPKIADFGMARIFGLDQTQDNTSRIVGTYGYMAPEYAMHGQFSMKSDVYSFGVLVLEIISGRKNSSFGESDGAQDLLTHAWRLWTNKKALDLVDPLIAENCQNSEVVRCIHIGLLCVQEDPAKRPAISTVFMMLTSNTVTLPVPRQPGFFIQCRAVKDPLDSDQSTTTKSFPASIDDESITDLYPR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
36	N-linked_Glycosylation	YLNHYCPNTTTYSSN ECCEECCCCCCCCCC	46.63	-
43	N-linked_Glycosylation	NTTTYSSNSTYSTNL CCCCCCCCCCCCCCH	32.22	-
61	N-linked_Glycosylation	LSSLSSRNASYSTGF HHHHHHCCCCCCCCC	34.88	-
70	N-linked_Glycosylation	SYSTGFQNATAGKAP CCCCCCCCCCCCCCC	36.68	-
104	N-linked_Glycosylation	NCVAFSVNQTLNLCP HCEEEECCHHHHCCH	28.11	-
178	N-linked_Glycosylation	EAAGKAANSSRKLYT HHHHHHHHCCCCEEE	45.43	-
247	N-linked_Glycosylation	YELYPFYNESAIETP EEEECCCCCCCCCCC	36.81	-
286	N-linked_Glycosylation	SLPGKSGNSTVLVVA CCCCCCCCCHHHHHH	41.41	-
424	Phosphorylation	GEERILVYEYMPNKS CCEEEEEEEECCCCC	9.63	-
480	Phosphorylation	IHRDLKASNILLDAD EECCHHHCCEEECCC	23.86	-
516	Phosphorylation	NTSRIVGTYGYMAPE CCCEEEEEEEECCCC	11.68	-
524	Phosphorylation	YGYMAPEYAMHGQFS EEECCCCHHHCCCCC	14.25	-
616	Phosphorylation	PAKRPAISTVFMMLT CCCCCCEEEEEEHHC	22.18	19880383
617	Phosphorylation	AKRPAISTVFMMLTS CCCCCEEEEEEHHCC	16.20	19880383
623	Phosphorylation	STVFMMLTSNTVTLP EEEEEHHCCCEEEEC	11.31	19880383
628	Phosphorylation	MLTSNTVTLPVPRQP HHCCCEEEECCCCCC	24.25	19880383
650	Phosphorylation	AVKDPLDSDQSTTTK EECCCCCCCCCCCCC	45.28	25561503
653	Phosphorylation	DPLDSDQSTTTKSFP CCCCCCCCCCCCCCC	32.48	25561503
654	Phosphorylation	PLDSDQSTTTKSFPA CCCCCCCCCCCCCCC	32.62	25561503
655	Phosphorylation	LDSDQSTTTKSFPAS CCCCCCCCCCCCCCC	37.16	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CRK6_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CRK6_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CRK6_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
P2C70_ARATH	KAPP	physical	7973632
FLS2_ARATH	FLS2	physical	26029224

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.