CRIP2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CRIP2_MOUSE
• UniProt AC: Q9DCT8
• Protein Name: Cysteine-rich protein 2
• Gene Name: Crip2
• Organism: Mus musculus (Mouse).
• Sequence Length: 208
• Protein Sequence: MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPQTEAPQVTGPIEVPVVRTEERKTSGPPKGPSKASSVTTFTGEPNMCPRCNKRVYFAEKVTSLGKDWHRPCLRCERCSKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDKDPEGTVQP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	S-nitrosocysteine	MASKCPKCDKTVYFA CCCCCCCCCCCEEHH	3.81	-
8	S-nitrosylation	MASKCPKCDKTVYFA CCCCCCCCCCCEEHH	3.81	21278135
8	S-palmitoylation	MASKCPKCDKTVYFA CCCCCCCCCCCEEHH	3.81	26165157
11	Phosphorylation	KCPKCDKTVYFAEKV CCCCCCCCEEHHHHH	13.74	-
13	Phosphorylation	PKCDKTVYFAEKVSS CCCCCCEEHHHHHHH	11.42	22817900
17	Ubiquitination	KTVYFAEKVSSLGKD CCEEHHHHHHHCCCC	43.94	-
17	Acetylation	KTVYFAEKVSSLGKD CCEEHHHHHHHCCCC	43.94	23806337
23	Acetylation	EKVSSLGKDWHKFCL HHHHHCCCCHHHHHH	64.04	23806337
38	Phosphorylation	KCERCNKTLTPGGHA HCCCCCCEECCCCCC	23.13	19367708
74	Phosphorylation	VNIGGAGSYIYEKPQ CEECCCCCCEECCCC	14.07	23737553
75	Phosphorylation	NIGGAGSYIYEKPQT EECCCCCCEECCCCC	13.45	26643407
77	Phosphorylation	GGAGSYIYEKPQTEA CCCCCCEECCCCCCC	15.07	26643407
82	Phosphorylation	YIYEKPQTEAPQVTG CEECCCCCCCCCCCC	42.51	23984901
88	O-linked_Glycosylation	QTEAPQVTGPIEVPV CCCCCCCCCCEEEEE	31.80	22517741
88	Phosphorylation	QTEAPQVTGPIEVPV CCCCCCCCCCEEEEE	31.80	26643407
98	Phosphorylation	IEVPVVRTEERKTSG EEEEEEECCCCCCCC	30.50	23375375
103	Phosphorylation	VRTEERKTSGPPKGP EECCCCCCCCCCCCC	45.17	23737553
104	Phosphorylation	RTEERKTSGPPKGPS ECCCCCCCCCCCCCC	52.95	23737553
112	Ubiquitination	GPPKGPSKASSVTTF CCCCCCCCCCCCEEE	56.26	-
114	Phosphorylation	PKGPSKASSVTTFTG CCCCCCCCCCEEECC	29.13	26239621
115	Phosphorylation	KGPSKASSVTTFTGE CCCCCCCCCEEECCC	28.48	25521595
117	Phosphorylation	PSKASSVTTFTGEPN CCCCCCCEEECCCCC	20.38	26239621
118	Phosphorylation	SKASSVTTFTGEPNM CCCCCCEEECCCCCC	19.62	26239621
120	Phosphorylation	ASSVTTFTGEPNMCP CCCCEEECCCCCCCC	38.24	23737553
126	S-nitrosocysteine	FTGEPNMCPRCNKRV ECCCCCCCCCCCCEE	2.15	-
126	S-nitrosylation	FTGEPNMCPRCNKRV ECCCCCCCCCCCCEE	2.15	21278135
126	S-palmitoylation	FTGEPNMCPRCNKRV ECCCCCCCCCCCCEE	2.15	28526873
138	Malonylation	KRVYFAEKVTSLGKD CEEEEEHHHHHCCCC	47.59	26320211
138	Acetylation	KRVYFAEKVTSLGKD CEEEEEHHHHHCCCC	47.59	23806337
138	Ubiquitination	KRVYFAEKVTSLGKD CEEEEEHHHHHCCCC	47.59	-
141	Phosphorylation	YFAEKVTSLGKDWHR EEEHHHHHCCCCCCC	37.80	29176673
144	Acetylation	EKVTSLGKDWHRPCL HHHHHCCCCCCCCCH	64.04	23806337
159	Phosphorylation	RCERCSKTLTPGGHA HCCCCCCEECCCCCC	21.41	27742792
161	Phosphorylation	ERCSKTLTPGGHAEH CCCCCEECCCCCCCC	25.72	30352176
176	Acetylation	DGQPYCHKPCYGILF CCCCCCCCCCEEEEE	32.97	7613535
190	Phosphorylation	FGPKGVNTGAVGSYI ECCCCCCCCCCCCEE	24.90	26643407
195	Phosphorylation	VNTGAVGSYIYDKDP CCCCCCCCEECCCCC	11.19	25521595
196	Phosphorylation	NTGAVGSYIYDKDPE CCCCCCCEECCCCCC	9.51	26643407
198	Phosphorylation	GAVGSYIYDKDPEGT CCCCCEECCCCCCCC	14.54	26643407
200	Acetylation	VGSYIYDKDPEGTVQ CCCEECCCCCCCCCC	59.20	21728379

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CRIP2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CRIP2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CRIP2_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of CRIP2_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.