| UniProt ID | CREL2_HUMAN | |
|---|---|---|
| UniProt AC | Q6UXH1 | |
| Protein Name | Cysteine-rich with EGF-like domain protein 2 | |
| Gene Name | CRELD2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 353 | |
| Subcellular Localization | Secreted . Endoplasmic reticulum . | |
| Protein Description | May regulate transport of alpha4-beta2 neuronal acetylcholine receptor.. | |
| Protein Sequence | MRLPRRAALGLLPLLLLLPPAPEAAKKPTPCHRCRGLVDKFNQGMVDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWWLQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPTQLPSREDL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 40 | Acetylation | RCRGLVDKFNQGMVD HHHHHHHHHHHHHHH | 38.44 | 27452117 | |
| 51 | Ubiquitination | GMVDTAKKNFGGGNT HHHHHHHHHCCCCCC | 55.86 | 29967540 | |
| 58 | O-linked_Glycosylation | KNFGGGNTAWEEKTL HHCCCCCCHHHHHHH | 36.10 | 55829805 | |
| 63 | Ubiquitination | GNTAWEEKTLSKYES CCCHHHHHHHHHCCC | 43.16 | 29967540 | |
| 64 | Phosphorylation | NTAWEEKTLSKYESS CCHHHHHHHHHCCCH | 39.27 | 23403867 | |
| 66 | Phosphorylation | AWEEKTLSKYESSEI HHHHHHHHHCCCHHH | 38.12 | 23403867 | |
| 68 | Phosphorylation | EEKTLSKYESSEIRL HHHHHHHCCCHHHHH | 20.05 | 23403867 | |
| 70 | Phosphorylation | KTLSKYESSEIRLLE HHHHHCCCHHHHHHH | 30.13 | 29255136 | |
| 70 (in isoform 5) | Phosphorylation | - | 30.13 | 24719451 | |
| 71 | Phosphorylation | TLSKYESSEIRLLEI HHHHCCCHHHHHHHH | 25.71 | 29255136 | |
| 103 | Ubiquitination | AQEEHLEAWWLQLKS HHHHHHHHHHHHHHH | 14.76 | 21963094 | |
| 144 | Phosphorylation | CLACQGGSQRPCSGN CEEECCCCCCCCCCC | 29.82 | - | |
| 149 | Phosphorylation | GGSQRPCSGNGHCSG CCCCCCCCCCCCCCC | 37.67 | - | |
| 187 | Phosphorylation | CMDGYFSSLRNETHS HHCCHHHHHCCCCCH | 22.81 | 24719451 | |
| 204 | Ubiquitination | TACDESCKTCSGLTN HHCCHHCCCCCCCCC | 62.94 | 21963094 | |
| 229 (in isoform 5) | Phosphorylation | - | 8.78 | - | |
| 236 (in isoform 5) | Phosphorylation | - | 41.30 | - | |
| 251 | N-linked_Glycosylation | AQFCKNANGSYTCEE HHHHHCCCCCEECCC | 49.70 | UniProtKB CARBOHYD | |
| 275 | Acetylation | GEGPGNCKECISGYA CCCCCCHHHHHHHHH | 60.67 | 7431077 | |
| 339 | O-linked_Glycosylation | PPAEAEATEGESPTQ CHHHHCCCCCCCCCC | 35.71 | OGP |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CREL2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CREL2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CREL2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SUV91_HUMAN | SUV39H1 | physical | 23455924 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
