dbPTM

CREG2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CREG2_HUMAN
UniProt AC	Q8IUH2
Protein Name	Protein CREG2
Gene Name	CREG2
Organism	Homo sapiens (Human).
Sequence Length	290
Subcellular Localization	Secreted .
Protein Description
Protein Sequence	MSVRRGRRPARPGTRLSWLLCCSALLSPAAGYVIVSSVSWAVTNEVDEELDSASTEEAMPALLEDSGSIWQQSFPASAHKEDAHLRPRAGAARARPPPAPPGMFSYRREGGQTASAPPGPRLRAATARSLAHASVWGCLATVSTHKKIQGLPFGNCLPVSDGPFNNSTGIPFFYMTAKDPVVADLMKNPMASLMLPESEGEFCRKNIVDPEDPRCVQLTLTGQMIAVSPEEVEFAKQAMFSRHPGMRKWPRQYEWFFMKMRIEHIWLQKWYGGASSISREEYFKAVPRKA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
106	Phosphorylation	APPGMFSYRREGGQT CCCCCCEEEECCCCC	11.48	-
165	N-linked_Glycosylation	PVSDGPFNNSTGIPF ECCCCCCCCCCCCCE	44.68	12408961
165	N-linked_Glycosylation	PVSDGPFNNSTGIPF ECCCCCCCCCCCCCE	44.68	12408961
166	N-linked_Glycosylation	VSDGPFNNSTGIPFF CCCCCCCCCCCCCEE	41.13	12408961
166	N-linked_Glycosylation	VSDGPFNNSTGIPFF CCCCCCCCCCCCCEE	41.13	12408961
276	Phosphorylation	KWYGGASSISREEYF HHHCCCCCCCHHHHH	24.85	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CREG2_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Reference
165	N	Glycosylation	12408961
It is not sure whether N-glycosylation is on Asn-165 and/or Asn-166.
166	N	Glycosylation	12408961
It is not sure whether N-glycosylation is on Asn-165 and/or Asn-166.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CREG2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CREG2_HUMAN !!

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CREG2_HUMAN

Related Literatures of Post-Translational Modification