CRD1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CRD1_ARATH
• UniProt AC: Q9M591
• Protein Name: Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, chloroplastic
• Gene Name: CRD1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 409
• Subcellular Localization: Plastid, chloroplast inner membrane; Peripheral membrane protein. Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
• Protein Description: Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)..
• Protein Sequence: MAAEMALVKPISKFSSPKLSNPSKFLSGRRFSTVIRMSASSSPPPPTTATSKSKKGTKKEIQESLLTPRFYTTDFEEMEQLFNTEINKNLNEAEFEALLQEFKTDYNQTHFVRNKEFKEAADKLQGPLRQIFVEFLERSCTAEFSGFLLYKELGRRLKKTNPVVAEIFSLMSRDEARHAGFLNKGLSDFNLALDLGFLTKARKYTFFKPKFIFYATYLSEKIGYWRYITIYRHLKENPEFQCYPIFKYFENWCQDENRHGDFFSALMKAQPQFLNDWQAKLWSRFFCLSVYVTMYLNDCQRTNFYEGIGLNTKEFDMHVIIETNRTTARIFPAVLDVENPEFKRKLDRMVVSYEKLLAIGETDDASFIKTLKRIPLVTSLASEILAAYLMPPVESGSVDFAEFEPNLVY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
38	Phosphorylation	FSTVIRMSASSSPPP CCEEEEHHCCCCCCC	18.36	28295753
40	Phosphorylation	TVIRMSASSSPPPPT EEEEHHCCCCCCCCC	24.84	28295753
48	Phosphorylation	SSPPPPTTATSKSKK CCCCCCCCCCCCCCC	33.44	28295753
50	Phosphorylation	PPPPTTATSKSKKGT CCCCCCCCCCCCCCC	34.30	28295753
51	Phosphorylation	PPPTTATSKSKKGTK CCCCCCCCCCCCCCH	32.25	28295753
53	Phosphorylation	PTTATSKSKKGTKKE CCCCCCCCCCCCHHH	39.09	28295753
64	Phosphorylation	TKKEIQESLLTPRFY CHHHHHHHHCCCCEE	16.59	25561503
67	Phosphorylation	EIQESLLTPRFYTTD HHHHHHCCCCEECCC	20.08	30291188
366	Phosphorylation	IGETDDASFIKTLKR HCCCCCHHHHHHHHC	34.20	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CRD1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CRD1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CRD1_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of CRD1_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.