CPT1B_MOUSE - dbPTM
CPT1B_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CPT1B_MOUSE
UniProt AC Q924X2
Protein Name Carnitine O-palmitoyltransferase 1, muscle isoform
Gene Name Cpt1b
Organism Mus musculus (Mouse).
Sequence Length 772
Subcellular Localization Mitochondrion outer membrane
Multi-pass membrane protein.
Protein Description
Protein Sequence MAEAHQAVAFQFTVTPDGVDFRLSREALRHIYLSGINSWKKRLIRIKNGILRGVYPGSPTSWLVVVMATVGSNYCKVDISMGLVDCIQRCLPERYGHFGTPQTEALLSMVIFSTGVWATGIFFFRQTLKLLLSYHGWMFEMHSKTSHATKIWAICVRLLSSRRPMLYSFQTSLPKLPVPSVPATIHRYLDSVRPLLDDEAYYRMETLAKEFQDKTAPRLQKYLVLKSWWATNYVSDWWEEYVYLRSRSPLMVNSNYYAMDFVLIKNTNVQAARLGNAVHAMIMYRRKLDREEIKPVMALGMVPMCSYQMERMFNTTRIPGKETDLLQHLSESRHVAVYHKGRFFKVWLYEGSRLLKPRDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAEARQTFFSSGKNKMSLDAIERAAFFVTLDEDSHCYNPDDETSLSLYGKALLHGNCYNRWFDKSFTLISCKNGLLGLNTEHSWADAPIIGHLWEFVLGTDTFHLGYTETGHCVGEPNTTLPPPQRLPWDIPEQCREAIENSYQVAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDKGKFCLTYEASMTRMFREGRTETVRSCTNESAAFVQAMMKGSHKKQDLQDLFRKASEKHQNMYRLAMTGAGIDRHLFCLYIVSKYLGVSSPFLAEVLSEPWSLSTSQIPQFQICMFDPKQYPNHLGAGGGFGPVADDGYGVSYMIAGENTMFFHISSKYSSSETNAQRFGNHIRQALLDIAELFKISKTDS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
41AcetylationSGINSWKKRLIRIKN
HCHHHHHHHHHHHCC		46.292394443
47UbiquitinationKKRLIRIKNGILRGV
HHHHHHHCCCEECCC		38.99-
86S-nitrosocysteineISMGLVDCIQRCLPE
ECHHHHHHHHHHCHH		1.91-
86S-nitrosylationISMGLVDCIQRCLPE
ECHHHHHHHHHHCHH		1.9121278135
155S-nitrosocysteineATKIWAICVRLLSSR
HHHHHHHHHHHHHCC		0.82-
155S-nitrosylationATKIWAICVRLLSSR
HHHHHHHHHHHHHCC		0.8221278135
160PhosphorylationAICVRLLSSRRPMLY
HHHHHHHHCCCCCEE		26.7925777480
161PhosphorylationICVRLLSSRRPMLYS
HHHHHHHCCCCCEEE		32.0725777480
206PhosphorylationEAYYRMETLAKEFQD
HHHHHHHHHHHHHHH		23.75-
209UbiquitinationYRMETLAKEFQDKTA
HHHHHHHHHHHHCCC		63.27-
305S-nitrosylationALGMVPMCSYQMERM
HCCCCCCCHHHHHHH		2.5421278135
305S-nitrosocysteineALGMVPMCSYQMERM
HCCCCCCCHHHHHHH		2.54-
321UbiquitinationNTTRIPGKETDLLQH
CCCCCCCCHHHHHHH		52.68-
330PhosphorylationTDLLQHLSESRHVAV
HHHHHHHHHCCCEEE		31.2523737553
332PhosphorylationLLQHLSESRHVAVYH
HHHHHHHCCCEEEEE		25.0623737553
349PhosphorylationRFFKVWLYEGSRLLK
CEEEEEEEECCCCCC		11.52-
352PhosphorylationKVWLYEGSRLLKPRD
EEEEEECCCCCCHHH		14.0723737553
372PhosphorylationQRILDDPSPPQPGEE
HHHHCCCCCCCCCHH		57.0928464351
380UbiquitinationPPQPGEEKLAALTAG
CCCCCHHHHHHHHCC		38.84-
401PhosphorylationEARQTFFSSGKNKMS
HHHHHHCCCCCCCCC		33.7123737553
402PhosphorylationARQTFFSSGKNKMSL
HHHHHCCCCCCCCCH		48.9423737553
404UbiquitinationQTFFSSGKNKMSLDA
HHHCCCCCCCCCHHH		56.17-
404AcetylationQTFFSSGKNKMSLDA
HHHCCCCCCCCCHHH		56.172394451
427S-nitrosocysteineTLDEDSHCYNPDDET
EECCCCCCCCCCCCC		3.98-
427S-nitrosylationTLDEDSHCYNPDDET
EECCCCCCCCCCCCC		3.9821278135
448S-nitrosocysteineKALLHGNCYNRWFDK
HHHHCCCCCHHHCCC		3.64-
448S-nitrosylationKALLHGNCYNRWFDK
HHHHCCCCCHHHCCC		3.6421278135
449PhosphorylationALLHGNCYNRWFDKS
HHHCCCCCHHHCCCC		16.2628464351
462S-nitrosocysteineKSFTLISCKNGLLGL
CCEEEEEECCCCCCC		2.92-
462S-nitrosylationKSFTLISCKNGLLGL
CCEEEEEECCCCCCC		2.9221278135
526S-nitrosocysteinePWDIPEQCREAIENS
CCCCCHHHHHHHHHH		3.96-
526S-nitrosylationPWDIPEQCREAIENS
CCCCCHHHHHHHHHH		3.9621278135
533PhosphorylationCREAIENSYQVAKAL
HHHHHHHHHHHHHHH		12.2627742792
534PhosphorylationREAIENSYQVAKALA
HHHHHHHHHHHHHHH		20.7027742792
548S-nitrosylationADDVELYCFQFLPFG
HCCCEEEEEECCCCC		3.1921278135
548S-nitrosocysteineADDVELYCFQFLPFG
HCCCEEEEEECCCCC		3.19-
586S-nitrosylationFRDKGKFCLTYEASM
HHHCCCEEEEEEHHH		2.9421278135
586S-nitrosocysteineFRDKGKFCLTYEASM
HHHCCCEEEEEEHHH		2.94-
602PhosphorylationRMFREGRTETVRSCT
HHHHCCCCCCHHHHC		47.0325159016
604PhosphorylationFREGRTETVRSCTNE
HHCCCCCCHHHHCHH		22.1725159016
608S-nitrosocysteineRTETVRSCTNESAAF
CCCCHHHHCHHHHHH		3.12-
608S-nitrosylationRTETVRSCTNESAAF
CCCCHHHHCHHHHHH		3.1221278135
621UbiquitinationAFVQAMMKGSHKKQD
HHHHHHHHCCCCHHC		44.15-
626UbiquitinationMMKGSHKKQDLQDLF
HHHCCCCHHCHHHHH		43.55-
766UbiquitinationLDIAELFKISKTDS-
HHHHHHHHHHCCCC-		59.71-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CPT1B_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CPT1B_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CPT1B_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of CPT1B_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CPT1B_MOUSE

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Related Literatures of Post-Translational Modification

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