CPNB1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CPNB1_ARATH
• UniProt AC: P21240
• Protein Name: Chaperonin 60 subunit beta 1, chloroplastic
• Gene Name: CPN60B1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 600
• Subcellular Localization: Plastid, chloroplast stroma .
• Protein Description: Binds RuBisCO small and large subunits and is implicated in the assembly of the enzyme oligomer. Involved in protein assisted folding. Required for proper plastid division..
• Protein Sequence: MASTFTATSSIGSMVAPNGHKSDKKLISKLSSSSFGRRQSVCPRPRRSSSAIVCAAKELHFNKDGTTIRRLQAGVNKLADLVGVTLGPKGRNVVLESKYGSPRIVNDGVTVAREVELEDPVENIGAKLVRQAAAKTNDLAGDGTTTSVVLAQGFIAEGVKVVAAGANPVLITRGIEKTAKALVTELKKMSKEVEDSELADVAAVSAGNNDEIGNMIAEAMSKVGRKGVVTLEEGKSAENNLYVVEGMQFDRGYISPYFVTDSEKMSVEFDNCKLLLVDKKITNARDLVGVLEDAIRGGYPILIIAEDIEQEALATLVVNKLRGTLKIAALRAPGFGERKSQYLDDIAILTGATVIREEVGLSLDKAGKEVLGNASKVVLTKETSTIVGDGSTQDAVKKRVTQIKNLIEQAEQDYEKEKLNERIAKLSGGVAVIQVGAQTETELKEKKLRVEDALNATKAAVEEGIVVGGGCTLLRLASKVDAIKATLDNDEEKVGADIVKRALSYPLKLIAKNAGVNGSVVSEKVLSNDNVKFGYNAATGKYEDLMAAGIIDPTKVVRCCLEHAASVAKTFLMSDCVVVEIKEPEPVPVGNPMDNSGYGY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
31	Phosphorylation	KKLISKLSSSSFGRR HHHHHHHHCCCCCCC	31.73	25561503
32	Phosphorylation	KLISKLSSSSFGRRQ HHHHHHHCCCCCCCC	40.20	25561503
33	Phosphorylation	LISKLSSSSFGRRQS HHHHHHCCCCCCCCC	26.72	25561503
101	Phosphorylation	VLESKYGSPRIVNDG EEEECCCCCEEECCC	14.12	-
205	Phosphorylation	LADVAAVSAGNNDEI HCHHHHHHCCCCHHH	26.23	29797451
262	Phosphorylation	SPYFVTDSEKMSVEF CCEEECCCCCEEEEE	29.74	19880383
340	Phosphorylation	PGFGERKSQYLDDIA CCCCCCHHHHHHHHH	30.22	22092075
362	Phosphorylation	IREEVGLSLDKAGKE HHHHHCCCCCHHHHH	28.70	19880383
384	Phosphorylation	VVLTKETSTIVGDGS EEEECCCEEEECCCC	19.75	29797451
478	Phosphorylation	CTLLRLASKVDAIKA HHHHHHHHHHCHHHH	37.49	30291188
519	Phosphorylation	KNAGVNGSVVSEKVL HHCCCCCEEEEEEEC	17.72	23328941
522	Phosphorylation	GVNGSVVSEKVLSND CCCCEEEEEEECCCC	29.55	28295753
546	Sulfoxidation	TGKYEDLMAAGIIDP CCCHHHHHHCCCCCH	3.57	25693801
566	Phosphorylation	CCLEHAASVAKTFLM HHHHHHHHHHHHHHC	24.32	30291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CPNB1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CPNB1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CPNB1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks.";
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.;
Plant Physiol. 150:889-903(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-478, AND MASSSPECTROMETRY.
PubMed: 19376835