dbPTM

COX7C_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	COX7C_HUMAN
UniProt AC	P15954
Protein Name	Cytochrome c oxidase subunit 7C, mitochondrial
Gene Name	COX7C
Organism	Homo sapiens (Human).
Sequence Length	63
Subcellular Localization	Mitochondrion inner membrane.
Protein Description	This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport..
Protein Sequence	MLGQSIRRFTTSVVRRSHYEEGPGKNLPFSVENKWSLLAKMCLYFGSAFATPFLVVRHQLLKT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MLGQSIRRFTTS ---CCCHHHHHHHHH	19.10	20068231
17	Phosphorylation	TTSVVRRSHYEEGPG HHHHHHHHHCCCCCC	21.62	20068231
25	Acetylation	HYEEGPGKNLPFSVE HCCCCCCCCCCCCHH	59.45	-
25	Succinylation	HYEEGPGKNLPFSVE HCCCCCCCCCCCCHH	59.45	-
25	Ubiquitination	HYEEGPGKNLPFSVE HCCCCCCCCCCCCHH	59.45	22817900
25	Succinylation	HYEEGPGKNLPFSVE HCCCCCCCCCCCCHH	59.45	21890473
34	Acetylation	LPFSVENKWSLLAKM CCCCHHHHHHHHHHH	25.34	25825284
34	Ubiquitination	LPFSVENKWSLLAKM CCCCHHHHHHHHHHH	25.34	22817900
34	2-Hydroxyisobutyrylation	LPFSVENKWSLLAKM CCCCHHHHHHHHHHH	25.34	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of COX7C_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of COX7C_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of COX7C_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of COX7C_HUMAN !!

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
DB02659	Cholic Acid

Regulatory Network of COX7C_HUMAN

Related Literatures of Post-Translational Modification