UniProt ID | COR1B_MOUSE | |
---|---|---|
UniProt AC | Q9WUM3 | |
Protein Name | Coronin-1B | |
Gene Name | Coro1b | |
Organism | Mus musculus (Mouse). | |
Sequence Length | 484 | |
Subcellular Localization | Cytoplasm, cytoskeleton. Localized to the leading edge in fibroblasts, as well as weakly along actin stress fibers.. | |
Protein Description | Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity).. | |
Protein Sequence | MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFMVLPLNKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIITWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITDEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPEAALEAEDWVSGQDANPILISLREAYVPSKQRDLKVSRRNVLSDSRPASYSRSGASTATAVTDVPSGNLAGAGEAGKLEEVMQELRALRMLVKEQGERISRLEEQLGRMENGDT | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
2 | Phosphorylation | ------MSFRKVVRQ ------CCHHHHHHH | 33.48 | 21844203 | |
25 | S-palmitoylation | QPVKNDQCYEDIRVS CCCCCCCCCCCEEEE | 4.47 | 28526873 | |
41 | S-palmitoylation | VTWDSTFCAVNPKFL EEECCCEEECCCCEE | 4.13 | 28526873 | |
209 | Phosphorylation | IIDPRRGTLVAEREK EECCCCCCEEEHHHH | 19.08 | 18779572 | |
303 | Phosphorylation | EITDEPPYIHFLNTF EECCCCCEEEEEECC | 20.11 | - | |
321 | Phosphorylation | EPQRGMGSMPKRGLE CCCCCCCCCCCCCCC | 24.02 | - | |
330 | Phosphorylation | PKRGLEVSKCEIARF CCCCCCCCHHHHHHH | 23.39 | 18779572 | |
332 | Glutathionylation | RGLEVSKCEIARFYK CCCCCCHHHHHHHHH | 3.40 | 24333276 | |
345 | S-nitrosylation | YKLHERKCEPIVMTV HHHHHCCCEEEEEEC | 10.61 | 20925432 | |
345 | S-nitrosocysteine | YKLHERKCEPIVMTV HHHHHCCCEEEEEEC | 10.61 | - | |
345 | S-palmitoylation | YKLHERKCEPIVMTV HHHHHCCCEEEEEEC | 10.61 | 28526873 | |
399 | Phosphorylation | LREAYVPSKQRDLKV EHHHHCCCCCCCCCC | 31.23 | 24719451 | |
400 | Malonylation | REAYVPSKQRDLKVS HHHHCCCCCCCCCCH | 43.19 | 26320211 | |
407 | Phosphorylation | KQRDLKVSRRNVLSD CCCCCCCHHHHHCCC | 24.76 | 24719451 | |
413 | Phosphorylation | VSRRNVLSDSRPASY CHHHHHCCCCCCCCC | 29.29 | 26824392 | |
415 | Phosphorylation | RRNVLSDSRPASYSR HHHHCCCCCCCCCCC | 36.47 | 21082442 | |
419 | Phosphorylation | LSDSRPASYSRSGAS CCCCCCCCCCCCCCC | 26.73 | 26824392 | |
420 | Phosphorylation | SDSRPASYSRSGAST CCCCCCCCCCCCCCC | 15.37 | 25777480 | |
421 | Phosphorylation | DSRPASYSRSGASTA CCCCCCCCCCCCCCC | 19.92 | 21082442 | |
421 | O-linked_Glycosylation | DSRPASYSRSGASTA CCCCCCCCCCCCCCC | 19.92 | 22517741 | |
423 | Phosphorylation | RPASYSRSGASTATA CCCCCCCCCCCCCEE | 32.54 | 25338131 | |
463 | Malonylation | RALRMLVKEQGERIS HHHHHHHHHHHHHHH | 40.12 | 26320211 | |
463 | Ubiquitination | RALRMLVKEQGERIS HHHHHHHHHHHHHHH | 40.12 | - | |
470 | Phosphorylation | KEQGERISRLEEQLG HHHHHHHHHHHHHHH | 36.71 | 26824392 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of COR1B_MOUSE !! |
Modified Location | Modified Residue | Modification | Function | Reference |
---|---|---|---|---|
2 | S | Phosphorylation |
| - |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of COR1B_MOUSE !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
Oops, there are no PPI records of COR1B_MOUSE !! |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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