COR1B_MOUSE - dbPTM
COR1B_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID COR1B_MOUSE
UniProt AC Q9WUM3
Protein Name Coronin-1B
Gene Name Coro1b
Organism Mus musculus (Mouse).
Sequence Length 484
Subcellular Localization Cytoplasm, cytoskeleton. Localized to the leading edge in fibroblasts, as well as weakly along actin stress fibers..
Protein Description Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity)..
Protein Sequence MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFMVLPLNKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIITWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITDEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPEAALEAEDWVSGQDANPILISLREAYVPSKQRDLKVSRRNVLSDSRPASYSRSGASTATAVTDVPSGNLAGAGEAGKLEEVMQELRALRMLVKEQGERISRLEEQLGRMENGDT
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSFRKVVRQ
------CCHHHHHHH
33.4821844203
25S-palmitoylationQPVKNDQCYEDIRVS
CCCCCCCCCCCEEEE
4.4728526873
41S-palmitoylationVTWDSTFCAVNPKFL
EEECCCEEECCCCEE
4.1328526873
209PhosphorylationIIDPRRGTLVAEREK
EECCCCCCEEEHHHH
19.0818779572
303PhosphorylationEITDEPPYIHFLNTF
EECCCCCEEEEEECC
20.11-
321PhosphorylationEPQRGMGSMPKRGLE
CCCCCCCCCCCCCCC
24.02-
330PhosphorylationPKRGLEVSKCEIARF
CCCCCCCCHHHHHHH
23.3918779572
332GlutathionylationRGLEVSKCEIARFYK
CCCCCCHHHHHHHHH
3.4024333276
345S-nitrosylationYKLHERKCEPIVMTV
HHHHHCCCEEEEEEC
10.6120925432
345S-nitrosocysteineYKLHERKCEPIVMTV
HHHHHCCCEEEEEEC
10.61-
345S-palmitoylationYKLHERKCEPIVMTV
HHHHHCCCEEEEEEC
10.6128526873
399PhosphorylationLREAYVPSKQRDLKV
EHHHHCCCCCCCCCC
31.2324719451
400MalonylationREAYVPSKQRDLKVS
HHHHCCCCCCCCCCH
43.1926320211
407PhosphorylationKQRDLKVSRRNVLSD
CCCCCCCHHHHHCCC
24.7624719451
413PhosphorylationVSRRNVLSDSRPASY
CHHHHHCCCCCCCCC
29.2926824392
415PhosphorylationRRNVLSDSRPASYSR
HHHHCCCCCCCCCCC
36.4721082442
419PhosphorylationLSDSRPASYSRSGAS
CCCCCCCCCCCCCCC
26.7326824392
420PhosphorylationSDSRPASYSRSGAST
CCCCCCCCCCCCCCC
15.3725777480
421PhosphorylationDSRPASYSRSGASTA
CCCCCCCCCCCCCCC
19.9221082442
421O-linked_GlycosylationDSRPASYSRSGASTA
CCCCCCCCCCCCCCC
19.9222517741
423PhosphorylationRPASYSRSGASTATA
CCCCCCCCCCCCCEE
32.5425338131
463MalonylationRALRMLVKEQGERIS
HHHHHHHHHHHHHHH
40.1226320211
463UbiquitinationRALRMLVKEQGERIS
HHHHHHHHHHHHHHH
40.12-
470PhosphorylationKEQGERISRLEEQLG
HHHHHHHHHHHHHHH
36.7126824392

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of COR1B_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference
2SPhosphorylation

-

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of COR1B_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of COR1B_MOUSE !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of COR1B_MOUSE

loading...

Related Literatures of Post-Translational Modification

TOP