dbPTM

COQ2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	COQ2_SCHPO
UniProt AC	Q10252
Protein Name	4-hydroxybenzoate polyprenyltransferase, mitochondrial {ECO:0000255\|HAMAP-Rule:MF_03189}
Gene Name	ppt1 {ECO:0000255\|HAMAP-Rule:MF_03189}
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	360
Subcellular Localization	Mitochondrion inner membrane Multi-pass membrane protein Matrix side .
Protein Description	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate..
Protein Sequence	MEMALLPQPSPARYFLRTPSWSAVAIFQAVKIKPLQLRTNSSNSVTPNLISPSKKSWKDLFSKRWQYYAEISRAGSPTGTYLLYSPCTWSILMAAYAYDSSLVNVTKMLALFGVGSFLMRSAGCVINDLWDRELDAKVERSKSRPLASGKLSVRQAISLLSVQLTASLGILLQLNPYTIKLGVASLVPVCIYPAMKRITYYPQVVLGLTFGYGAVMGWPALAGEACMNWSVVAPLYLSTISWIVLYDTIYAHQDKRDDVKANIYSTALRFGDNTKPVLCGLAALQIATLATAGIMNGQGPVFYTLGVAGAAYRLSSMIYKVDLDDPKDCFRWFKRNSNTGYLVAAAIALDWLAKSFIYDS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of COQ2_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of COQ2_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of COQ2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of COQ2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
DAD3_SCHPO	dad3	genetic	23365689

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of COQ2_SCHPO

Related Literatures of Post-Translational Modification