| UniProt ID | COPB_SCHPO | |
|---|---|---|
| UniProt AC | Q9UUF7 | |
| Protein Name | Coatomer subunit beta | |
| Gene Name | sec26 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 940 | |
| Subcellular Localization |
Cytoplasm . Golgi apparatus membrane Peripheral membrane protein Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane Peripheral membrane protein Cytoplasmic side. The coatomer is cytoplasmic or polymerized on the cytoplasmic side |
|
| Protein Description | The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).. | |
| Protein Sequence | MSCWTLVQQDFLEAPSVDALKTSLESKNDYVKISAMKTILRVVINGDSLPSILMHVIRFVMPSRNKELKKLLYYYWEVCPKYNNDGTMKQEMILACNSFRNDLQHPNEFIRGATLRFLCKLKEPELLDPLIPTVRQCLEHRHAYVRKNAILAVFSIYQVSNHLIPDAASLAEDFLAAESEGTCKRNALIVLFTIDPEKAKAWLLANFEQIPSLNASSLLVIIEFIRKVVLTKADGLEKLRFQSLLVSLTATNNSSVVFEAATSVINVFPDAESLKLAASRLLALADREADNNAKLIMLDRISQLAARDKSILEDLITDVIPFLSSSDFDVCEKAISIIMGLVSSRNVEDILNHFQKELTKSNGETEKDDGRRRALTKAIHSCAINFPHTAATAIQYLLSHISDFQSKSASSVLSFIKEVMEKFPDLRSSNITKLLLSLKELRAGKIFRGVIWIAGEYCLTEDDIRVAWKSIRASLGEVPILASEEQLLKDVSNVPEDDLLIDISAPASTSRKVLPDGTYATESAVTSEALSAARLEAVKASKKPPLRTQILSGDYYLAAVLASALTKLVMRFARLSFDKERLNALKAEACLIMTSIIRVGQSKFVKYTIDDDSVERIMNCIRAIYSFEELPEFQTVFLDDMRKAFSSLVAQSDKRQKEADLLVNGSDAVQADELLNIRQFQRVIEEKQDLNFESDIIQATNDGMVVEDLASKLDHIVQLAGFTDPVYCEAYVKIQQFDIILDILLVNRTDTTLQNLSVDLATLGDLKVVERPPPMNLGPHAFKSVQATVKVSSTESAVIFGNIVYGGKASDEDKIVVLNGIPVNIIDYIKPAFIPESQFRSMWTEFEWENKVDISSNEDISLYDFLHKIMKKTNMNCLTPDASLRGDCGFLSANLYACSIFGEDALMSLSVEKSVSGPISGHVRIRSKTQGIALSLGAFV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 408 | Phosphorylation | ISDFQSKSASSVLSF HHHHCCCCHHHHHHH | 38.33 | 25720772 | |
| 527 | Phosphorylation | ATESAVTSEALSAAR CCHHHHCHHHHHHHH | 17.80 | 29996109 | |
| 914 | Phosphorylation | MSLSVEKSVSGPISG HCCEEEECCCCCCCC | 14.17 | 25720772 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of COPB_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of COPB_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of COPB_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of COPB_SCHPO !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
