COPB2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: COPB2_SCHPO
• UniProt AC: O42937
• Protein Name: Probable coatomer subunit beta'
• Gene Name: sec27
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 796
• Subcellular Localization: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. The coatomer is cytoplasmic or polymerized on the cytoplasmic side o
• Protein Description: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity)..
• Protein Sequence: MMRLDFQRKLLSHTERVKAVDFHPTEPWVIASHYNGQVGIWNYNTQTLVRSFDINDVPIRACAFIARKNWFVCGSDDFQVRVYNYNTGEKVTQFEAHPDYIRALVVHPTQPFLLTSSDDMTIKCFNWDMSWKCVQTFEGHSRYVMSLAINPKDTNTFASSCLDGTVKVWSFGSSVANFTLQAHDRGVNYVNYYPAGDKPYLITAGDDNLIKVWDYQTKACVRILEGHTNNVSFAFFHSKFPIIISGSEDGTVKIWHTLSYSLIKSYNFSLDRAWCIAQNKDNGLVTVGFDNGLITFSLGRDEPSVTMDSSGKVVWSNYNEVMSAMIRPAKEQSDLTDGSLISLSVKELGTTELYPAVLKHSPNGRFVSVCGNGEYIVYTALAWRNKAYGKALDFAWSADSNVYGSRTSDRSIVIHKNFKESNRLDLSYSCDKIFGGFLLGVVGSDFICFYDWDTGILVRKIDVKPKGVYWNDDGRFVILACDDDFYLLGFNAEMFYSAVESGTADEEEGVADSFEALADVSESVVNGKWVAETFIYTTTAARLNYLIGDQTYKIANVESSFYLLGYIPRDDRIYLTDRDMNVVSYSFNLAIIEYQSLVLKGDLEAAQGLLEQISETDRPRLSDFLSRLGYKEAALELSGDSVQRFELALDAQRLDIASQIAQELDDPLKWRSLGDAALNAWDFVLAQECFEKGKDYGSLVLLYTATNNHEGLKELSQLTKSTKINNTAFICSWLTNQPAECVNILTSTQRYPEANLFAATYCPDEVKNVLPEWKVDLTKNQKERIADSLGDLELKN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	Phosphorylation	NTQTLVRSFDINDVP CCCCEEEEECCCCCC	21.57	25720772
788	Phosphorylation	QKERIADSLGDLELK HHHHHHHHHCCCCCC	25.82	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of COPB2_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of COPB2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of COPB2_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of COPB2_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.