dbPTM

COG6_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	COG6_DROME
UniProt AC	Q9V564
Protein Name	Conserved oligomeric Golgi complex subunit 6
Gene Name	CG1968
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	630
Subcellular Localization	Golgi apparatus membrane Peripheral membrane protein.
Protein Description	Required for normal Golgi function..
Protein Sequence	MSSTQEKPEELDRIQKRVNKILEARLESDKDTLDALSGLSTFFTENTLQNRRNLRSQIEHRSVGINENFLKAFRQVKLSLDAVCEDLDTMATSVETMKSDLETSKALTKDLIKQTNTMQRERDRLEVHKQIAQAFLARFQLSGAEHQLLYGAAKDAPIVADFFRVLDRVQSIHADCRLLMQCGYQTAAIDIMEEMTLHQEGALERLYRWTQNHCRSLENNEIGPLIVEAMSRLQDRPVLFKYVIDEYAIARRAVLVRQFIEALTEGGPGGNPKPIELHAHDPKRYIGDMFAWLHQSIPTEKENLSLLFKKCDKQDISDQLQNALGYIADGVCHPLKVRVETILQAEKDTIVLFTISNLLRFYQQIMRQVVQGGSLEECLVELQKSSEQIYLGALAAQVRSVLQRPSGGSGLALEPPQRDLVPPPSVARLLNMLKEILSVATMVDGRQADITKIVSCVIDPLLQSVQESAAHLPTVDMGVYLLNCLHHMQSSLAVYEYMDERVERLQAQSDAQLDTLTSEQASSLVANLNLGPIYAILQSNQSKIETNLLKIFMSKMDAFLELPDVLLLPQVQLIMSSSHRAAVQKRSFNVIVAIYKQIYERVHDPANGFEQPEQLLHRTPEQVAHILTST

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
406	Phosphorylation	RSVLQRPSGGSGLAL HHHHCCCCCCCCCCC	58.96	21082442
409	Phosphorylation	LQRPSGGSGLALEPP HCCCCCCCCCCCCCC	33.87	22817900
546	Phosphorylation	SNQSKIETNLLKIFM CCHHHHHHHHHHHHH	34.34	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of COG6_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of COG6_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of COG6_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CSN7_DROME	CSN7	physical	14605208
CCDCX_DROME	CG32809	physical	14605208
BAP60_DROME	Bap60	physical	14605208
EXOC3_DROME	Sec6	physical	14605208
NDC1_DROME	Ndc1	physical	14605208

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of COG6_DROME

Related Literatures of Post-Translational Modification