COG2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: COG2_MOUSE
• UniProt AC: Q921L5
• Protein Name: Conserved oligomeric Golgi complex subunit 2
• Gene Name: Cog2
• Organism: Mus musculus (Mouse).
• Sequence Length: 731
• Subcellular Localization: Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
• Protein Description: Required for normal Golgi morphology and function..
• Protein Sequence: MEKRRMNLPTGPDTLCFDKDEFMKEDFDVDHFVSDCRKRVQLEELRDDLELYYKLLKTAMVELINKDYADFVNLSTNLVGMDRALNQLSVPLGQLREEVLSLRSSVSEGILAVDERMSKQEDIRKKKMSVLRLIQVIRSVEKIEKILNSQSSKDVSSQEASSPLLTGQVLERIATEFNQLQFHAVQSKGMPLLDKVRPRIAGITAMLQQSLEGLLLEGLQTSDVDIVRHCLRTYATIDKTQDAEALVGQVLVKPYVNEVIVEQFVESHPSSLQLMYNKLLEFVPHHCRLLREVTGGAVSSEKGTIVPGYDFLVNSVWPEIVRGLEEKLPSLFNPGDPDAFHQKYTVSMDFVQRFERQCGSQASVKRLRAHPAYHNFSNKWNLPVYFQIRFREVAGSLEAALTDGLEDAPAGSPYCLLASHRTWISLGKCWSDEMFLPLLAHRLWRLTLQILARFSVFVSELSVRPVSNESAKETKKPLTGSKDPSEDQGSHASEASAASISSTQLVYVVSDLGRLQEWLPDLLETVKQKLEMIGFKNFSSISAALEDSQSALSAHVPALSSRIVQDLSESCFSYLKSALEVPRLYRRTNKEVPSTASSYVDSALKPLYQLQSGHGDKVQPAVMQSWLQEALSDSTHRYFETVSDVLNSVKKMEESLKRLKQARRSPATNPVSSSGGGMSDDDKIRLQLALDVEHLGEQIQRMGLQTSDIKSFPALMELVLAARDQAAAEQP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
161	Phosphorylation	DVSSQEASSPLLTGQ CCCCCHHCCCHHHHH	31.56	28066266
162	Phosphorylation	VSSQEASSPLLTGQV CCCCHHCCCHHHHHH	26.98	28066266
166	Phosphorylation	EASSPLLTGQVLERI HHCCCHHHHHHHHHH	33.00	28066266
385	Phosphorylation	NKWNLPVYFQIRFRE CCCCCCEEEEEEHHH	6.45	24759943
599	Phosphorylation	VPSTASSYVDSALKP CCCCHHHHHHHHHHH	13.04	28576409
648	Phosphorylation	TVSDVLNSVKKMEES HHHHHHHHHHHHHHH	31.02	30352176
665	Phosphorylation	RLKQARRSPATNPVS HHHHHHHCCCCCCCC	17.21	24899341
668	Phosphorylation	QARRSPATNPVSSSG HHHHCCCCCCCCCCC	43.36	28066266

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of COG2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of COG2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of COG2_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of COG2_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.