| UniProt ID | COG1_MOUSE | |
|---|---|---|
| UniProt AC | Q9Z160 | |
| Protein Name | Conserved oligomeric Golgi complex subunit 1 | |
| Gene Name | Cog1 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 980 | |
| Subcellular Localization |
Golgi apparatus membrane Peripheral membrane protein Cytoplasmic side. |
|
| Protein Description | Required for normal Golgi function.. | |
| Protein Sequence | MAAATASSALKRLDLRDPNALFETHGAEEIRGLERQVRAEIEHKKEELRQMVGERYRDLIEAADTIGQMRRCAEGLVDAVQATDQYCARLRQAGSVAPRVPRAPQPQPPSEKFYSMAAQIKLLLEIPEKIWSAMEASQHLQATQLYLLCCHLHSLLQLDSSNSRYSPILSRFPILIRQVAAASHFRSTILHESKMLLKCQAVSDQAVAEALCSIMLLEESSPRQALTDFLLARKATIQTLLNQSHHGAGIKAQICSLVELLATTLNQAHALFYTLPEGVLPDPSLPCGLLFSTLETVTRQHPTGKGIGALQGEMKLCSWFRHLPTSIIEFQPTLRTLAHPISQEYLKDTLQKWIDMCNEDIKNGIGNLLMYVKSMKGLAGIRDAIWDLLSNESASHSWEVVCQRLLEKPLLFWEDLMQQLFLDRLQTLTREGFESISNSSKELLVSALQELETNNSTSNKHVHFEQNMSFFLWSESPNDLPSDAAWVSVANRAQFASSGLSMKAQAISPCVQNFCSALDSKLKVKLDDLLAYLPSSDTPLLKDTTPTHQPKNSAFDRYADAGTVQDMLRTQSVACIKSVVGCIQAELCTIEEVTREQKDVLHSTKLHAVLFMARLCQSLGELCPHLKQCVVGQCGGSEKPAREARALKKQGKGRAQDVLPAQAQWQGVKEVLLQQSVMAYRVWSTALVKFLICGFTRSLLLRDAGSVLATATNWDELEIQEETESGSSVTSKIRLPTQPSWYVQSFLFSLCQEVNRVGGHALPKVTLQEMLKTCMAQVIAAYEQLTEENQIKKEGAFPMTQNRALQLLYDLRYLTMVLSSKGEEVKSGRSKADSRMEKMTERLEALIDPFDLDVFTPHLNSNLNRLVQRTSVLFGLVTGTENQFASRSSTFNSQEPHNILPLASSQIRFGLLPLSMTSTRKARATSRSVETQAQVGPPALSRVGDPTTHPGSLFRQLASEEDDSPAPSLFKLAWLSSMTK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MAAATASSA ------CCCHHHHHH | 13.05 | - | |
| 7 | Phosphorylation | -MAAATASSALKRLD -CCCHHHHHHHHHCC | 16.28 | 25338131 | |
| 8 | Phosphorylation | MAAATASSALKRLDL CCCHHHHHHHHHCCC | 34.85 | 29514104 | |
| 115 | Phosphorylation | PPSEKFYSMAAQIKL CCCHHHHHHHHHHHH | 12.70 | 30482847 | |
| 342 | Phosphorylation | RTLAHPISQEYLKDT HHHCCCCCHHHHHHH | 22.78 | - | |
| 544 | Phosphorylation | DTPLLKDTTPTHQPK CCCCCCCCCCCCCCC | 32.84 | 29899451 | |
| 547 | Phosphorylation | LLKDTTPTHQPKNSA CCCCCCCCCCCCCCC | 30.93 | 29899451 | |
| 598 | Acetylation | EEVTREQKDVLHSTK HHHCHHHHHHHHHHH | 45.08 | 23806337 | |
| 598 | Malonylation | EEVTREQKDVLHSTK HHHCHHHHHHHHHHH | 45.08 | 26320211 | |
| 800 | Phosphorylation | KEGAFPMTQNRALQL HCCCCCCCHHHHHHH | 23.95 | 29899451 | |
| 809 | Phosphorylation | NRALQLLYDLRYLTM HHHHHHHHHHHHHHH | 22.86 | 29899451 | |
| 928 | Phosphorylation | KARATSRSVETQAQV HHHHCCCCHHHHHCC | 24.87 | 25338131 | |
| 959 | Phosphorylation | SLFRQLASEEDDSPA HHHHHHHCCCCCCCC | 50.54 | 30635358 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of COG1_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of COG1_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of COG1_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of COG1_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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