COE3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: COE3_MOUSE
• UniProt AC: O08791
• Protein Name: Transcription factor COE3
• Gene Name: Ebf3
• Organism: Mus musculus (Mouse).
• Sequence Length: 596
• Subcellular Localization: Nucleus .
• Protein Description: Transcriptional activator. [PubMed: 9151732 Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity]
• Protein Sequence: MFGIQENIPRGGTTMKEEPLGSGMNPVRSWMHTAGVVDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVDFVEKEKEPNNEKTNNGIHYKLQLLYSNGVRTEQDLYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTAPSYLENATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVVFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFVYTALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVLLKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQIPTLGNTPAHTGMMGVNSFSSQLAVNVSETSQANDQVGYSRNTSSVSPRGYVPSSTPQQSNYNTVSTSMNGYGSGAMANLGVPGSPGFLNGSSANSPYGIVPSSPTMAASSVTLPSNCSSTHGIFSFSPANVISAVKQKSAFAPVVRPQASPPPSCTSANGNGLQAMSGLVVPPM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
250	Phosphorylation	RARRLDPSEGTAPSY CCCCCCCCCCCCCHH	48.61	-
253	Phosphorylation	RLDPSEGTAPSYLEN CCCCCCCCCCHHHHH	31.20	-
256	Phosphorylation	PSEGTAPSYLENATP CCCCCCCHHHHHCCC	39.63	-
257	Phosphorylation	SEGTAPSYLENATPC CCCCCCHHHHHCCCC	19.58	-
346	Phosphorylation	APGRFVYTALNEPTI CCCCEEEEECCCCCC	21.26	-
355	Phosphorylation	LNEPTIDYGFQRLQK CCCCCCCHHHHHHHH	18.91	-
464	Phosphorylation	QVGYSRNTSSVSPRG CCCCCCCCCCCCCCC	22.67	28066266
465	Phosphorylation	VGYSRNTSSVSPRGY CCCCCCCCCCCCCCC	32.09	28066266
466	Phosphorylation	GYSRNTSSVSPRGYV CCCCCCCCCCCCCCC	25.28	28066266
468	Phosphorylation	SRNTSSVSPRGYVPS CCCCCCCCCCCCCCC	15.72	28066266

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of COE3_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of COE3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of COE3_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
COE4_MOUSE	Ebf4	physical	20211142

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.