dbPTM

COCH_CHICK - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	COCH_CHICK
UniProt AC	O42163
Protein Name	Cochlin
Gene Name	COCH
Organism	Gallus gallus (Chicken).
Sequence Length	547
Subcellular Localization	Secreted .
Protein Description	Plays a role in the control of cell shape and motility in the trabecular meshwork..
Protein Sequence	MQFAPLLLGVFLLCGSARGSDSSASNAITCFTRGLDLRKETEDVLCPANCPLWQFYVFGDGIYASLSSVCGAAIHRGVITNAGGAVRVQTLPGQENYPAVHANGIQSQVLSRWASSFSVTPGTNNLALEAVGRSVATARPATGKRPKKTLEKKAGNKDCKADIAFLIDGSYNIGQRRFNLQKNFVGKVAVMLGIGTEGPHVGVVQASEHPKIEFYLKNFTAAKEVLFAIKELGFRGGNSNTGKALKHAAQKFFSMENGARKGIPKIIVVFLDGWPSDDLEEAGIVAREFGVNVFIVSVAKPTTEELGMVQDIGFIDKAVCRNNGFFSYQMPSWFGTTKYVKPLVQKLCSHEQMLCSKTCYNSVNIGFLIDGSSSVGESNFRLMLEFISNVAKAFEISDIGSKIATVQFTYDQRTEFSFTDYTTKEKVLSAIRNIRYMSGGTATGDAISFTTRNVFGPVKDGANKNFLVILTDGQSYDDVRGPAVAAQKAGITVFSVGVAWAPLDDLKDMASEPRESHTFFTREFTGLEQMVPDVIRGICKDFLDSKQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
218	N-linked_Glycosylation	KIEFYLKNFTAAKEV CEEEEECCCHHHHHH	36.58	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of COCH_CHICK !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of COCH_CHICK !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of COCH_CHICK !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of COCH_CHICK !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of COCH_CHICK

Related Literatures of Post-Translational Modification