dbPTM

CNTFR_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CNTFR_RAT
UniProt AC	Q08406
Protein Name	Ciliary neurotrophic factor receptor subunit alpha
Gene Name	Cntfr
Organism	Rattus norvegicus (Rat).
Sequence Length	372
Subcellular Localization	Cell membrane Lipid-anchor, GPI-anchor.
Protein Description	Binds to CNTF. The alpha subunit provides the receptor specificity..
Protein Sequence	MAASVPWACCAVLAAAAAAVYTQKHSPQEAPHVQYERLGTDVTLPCGTASWDAAVTWRVNGTDLAPDLLNGSQLILRSLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFYCSWHLSAPTYIPNTFNVTVLHGSKMMVCEKDPALKNRCHIRYMHLFSTIKYKVSISVSNALGHNTTAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSNGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHATPWTEEPRHLTTEAQAPETTTSTTSSLAPPPTTKICDPGELSSGGGPSIPFLTSVPVTLVLAAAAATANNLLI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
60	N-linked_Glycosylation	AAVTWRVNGTDLAPD EEEEEEECCCCCCHH	38.79	-
70	N-linked_Glycosylation	DLAPDLLNGSQLILR CCCHHHCCCCHHHHH	56.20	-
142	N-linked_Glycosylation	TYIPNTFNVTVLHGS CCCCCCCEEEEEECC	26.89	-
190	N-linked_Glycosylation	VSNALGHNTTAITFD ECCCCCCCCEEEEEE	37.01	-
261	N-linked_Glycosylation	WQHVELSNGTAHTIT CEEEECCCCCEEEEE	65.54	-
342	GPI-anchor	CDPGELSSGGGPSIP CCCCCCCCCCCCCCC	54.82	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CNTFR_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CNTFR_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CNTFR_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CNTFR_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CNTFR_RAT

Related Literatures of Post-Translational Modification