CNT6_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CNT6_SCHPO
• UniProt AC: Q10165
• Protein Name: Probable ribosylation factor GTPase-activating protein cnt6
• Gene Name: cnt6
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 923
• Subcellular Localization: Cytoplasm . Cell tip . Cell septum .
• Protein Description: GTPase-activating protein for the ADP ribosylation factor family..
• Protein Sequence: MDGSDSLLKSVDVSKLDNGSTISFRAREDGFLESISSSSGKLVDMVLDSTSKECLPKFSFQNKLDFYFLFSDRVLQLQKERKVLVLIHCESLQSFDSFFAQKLKYADLISSDNVHEIFLPDSNAANIRYHWEWSPPSGKLLEYECKNYSCIAVYSTEDCTLERISKFSYYTVSRCGDSMDDTFFSESQRVTSPLTTSQTVQTQPPQSPEAKTELSLINTKTVIFPENYEDGPSFRSMLHELEQKSSLMKYYCKKIMKRIVQLSDAYDASQVAVMKLSETLSEASNSTSMNMDILLDSYLTKAMDIHATFIQKLNYDLINLLYEPFHNIYSSFIKPIDDRRLEFDEQSKSFYGSLSRYLSAKKDKKGGDSKFFQKEKTFALQRYDYYCFMQDLHDGSIINDINGIFLQYFHRQYDHIALFSNLMNSVLPNLQQLNLKLEKTKWSTTRRDKGREMHRSQVIQTSGRPKSMAPPSPSPISPSFPLHEIQSPMPNRRMAASADDISQTSNFTTEIKGKCISNGGSASPDKIFKEGLLLVFGATELGTDLAMVSKAAWHKHWIVVENGSLWEYANWKDSVKSNVSSISLKHASADKVRKQGRRFCFEVVTPKLKRLYQATSAEEMDSWIEAICEAAKISSFQLSRVATPLSASVRRPSKVFPLFSTSFETTPISRKLSGSGIKKAFSRKGSWNLQQFFRSDNSGTMHMEQLERYHASANIFIQMLRKTDVSNSVCADCGSVKDVTWCSINIPVVLCIECSGIHRSLGTHISKTRSLLLDSLSQQSKVLLCKIGNAAVNRVYEKGLSNPSLKPKPEHNAQVKLAFAQKKYVEHAFIDFAGVDADATLLEGLEQNKISKILLGLAAKPNFEENGVVFLKAVTRDTSKLHLLELLFMNGLLLPDSEQLSEHVSPDMQSYLSQKQFTKYLKE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
191	Phosphorylation	FSESQRVTSPLTTSQ CCCCCCCCCCCCCCC	27.15	25720772
192	Phosphorylation	SESQRVTSPLTTSQT CCCCCCCCCCCCCCC	18.30	28889911
195	Phosphorylation	QRVTSPLTTSQTVQT CCCCCCCCCCCCEEC	27.99	25720772
196	Phosphorylation	RVTSPLTTSQTVQTQ CCCCCCCCCCCEECC	26.90	29996109
207	Phosphorylation	VQTQPPQSPEAKTEL EECCCCCCCCCCCEE	30.40	28889911
467	Phosphorylation	QTSGRPKSMAPPSPS ECCCCCCCCCCCCCC	23.90	29996109
497	Phosphorylation	PNRRMAASADDISQT CCCCCCCCHHHHHHC	23.77	28889911
523	Phosphorylation	ISNGGSASPDKIFKE ECCCCCCCHHHHHHC	35.02	27738172
639	Phosphorylation	KISSFQLSRVATPLS CCCCEEHHCCCCCCC	17.58	25720772
643	Phosphorylation	FQLSRVATPLSASVR EEHHCCCCCCCCCCC	23.16	29996109
646	Phosphorylation	SRVATPLSASVRRPS HCCCCCCCCCCCCCH	21.50	25720772
648	Phosphorylation	VATPLSASVRRPSKV CCCCCCCCCCCCHHC	16.87	25720772
653	Phosphorylation	SASVRRPSKVFPLFS CCCCCCCHHCCCCCC	39.37	25720772
660	Phosphorylation	SKVFPLFSTSFETTP HHCCCCCCCCCCCCC	30.72	25720772
661	Phosphorylation	KVFPLFSTSFETTPI HCCCCCCCCCCCCCC	30.05	21712547
662	Phosphorylation	VFPLFSTSFETTPIS CCCCCCCCCCCCCCC	21.64	21712547
665	Phosphorylation	LFSTSFETTPISRKL CCCCCCCCCCCCCCC	35.54	21712547
669	Phosphorylation	SFETTPISRKLSGSG CCCCCCCCCCCCCCC	25.27	21712547
673	Phosphorylation	TPISRKLSGSGIKKA CCCCCCCCCCCCHHH	33.67	24763107
675	Phosphorylation	ISRKLSGSGIKKAFS CCCCCCCCCCHHHHH	33.69	29996109
686	Phosphorylation	KAFSRKGSWNLQQFF HHHHCCCCCCHHHHH	18.80	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CNT6_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CNT6_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CNT6_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of CNT6_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-207, AND MASSSPECTROMETRY.
PubMed: 18257517