dbPTM

CNBP1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CNBP1_MOUSE
UniProt AC	Q9JJN6
Protein Name	Beta-catenin-interacting protein 1
Gene Name	Ctnnbip1
Organism	Mus musculus (Mouse).
Sequence Length	81
Subcellular Localization	Cytoplasm. Nucleus.
Protein Description	Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway..
Protein Sequence	MNREGAPGKSPEEMYIQQKVRVLLMLRKMGSNLTASEEEFLRTYAGVVSSQLSQLPQHSIDQGAEDVVMAFSRSETEDRRQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Acetylation	NREGAPGKSPEEMYI CCCCCCCCCHHHHHH	62.87	15628213
10	Phosphorylation	REGAPGKSPEEMYIQ CCCCCCCCHHHHHHH	43.38	22817900
19	Ubiquitination	EEMYIQQKVRVLLML HHHHHHHHHHHHHHH	18.68	27667366
19	Acetylation	EEMYIQQKVRVLLML HHHHHHHHHHHHHHH	18.68	22826441
31	Phosphorylation	LMLRKMGSNLTASEE HHHHHHCCCCCCCHH	25.76	22817900
43	Phosphorylation	SEEEFLRTYAGVVSS CHHHHHHHHHHHHHH	21.63	26643407
44	Phosphorylation	EEEFLRTYAGVVSSQ HHHHHHHHHHHHHHH	8.57	26643407
49	Phosphorylation	RTYAGVVSSQLSQLP HHHHHHHHHHHHCCC	15.23	26643407
50	Phosphorylation	TYAGVVSSQLSQLPQ HHHHHHHHHHHCCCC	24.43	26643407
53	Phosphorylation	GVVSSQLSQLPQHSI HHHHHHHHCCCCCCC	23.26	26643407
59	Phosphorylation	LSQLPQHSIDQGAED HHCCCCCCCCCCHHH	23.71	27180971

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CNBP1_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CNBP1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CNBP1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
CTNB1_MOUSE	Ctnnb1	physical	10898789

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CNBP1_MOUSE

Related Literatures of Post-Translational Modification