CMTA5_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CMTA5_ARATH
• UniProt AC: O23463
• Protein Name: Calmodulin-binding transcription activator 5 {ECO:0000303|PubMed:11925432}
• Gene Name: CAMTA5 {ECO:0000303|PubMed:11925432}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 923
• Subcellular Localization: Nucleus .
• Protein Description: Transcription activator. [PubMed: 14581622 Binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3' (By similarity Regulates transcriptional activity in response to calcium signals (Probable Binds calmodulin in a calcium-dependent manner (By similarity Involved in response to cold. Contributes together with CAMTA3 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2]
• Protein Sequence: MAGVDSGKLIGSEIHGFHTLQDLDIQTMLDEAYSRWLRPNEIHALLCNHKFFTINVKPVNLPKSGTIVLFDRKMLRNFRKDGHNWKKKKDGKTIKEAHEHLKVGNEERIHVYYAHGEDTPTFVRRCYWLLDKSQEHIVLVHYRETHEVHAAPATPGNSYSSSITDHLSPKIVAEDTSSGVHNTCNTGFEVRSNSLGSRNHEIRLHEINTLDWDELLVPADISNQSHPTEEDMLYFTEQLQTAPRGSVKQGNHLAGYNGSVDIPSFPGLEDPVYQNNNSCGAGEFSSQHSHCGVDPNLQRRDFSATVTDQPGDALLNNGYGSQDSFGRWVNNFISDSPGSVDDPSLEAVYTPGQDSSTPPTVFHSHSDIPEQVFNITDVSPAWAYSTEKTKILVTGFFHDSFQHLGRSNLICICGELRVPAEFLQMGVYRCFLPPQSPGVVNLYLSVDGNKPISQLFSFEHRSVQFIEKAIPQDDQLYKWEEFEFQVRLAHLLFTSSNKISVLTSKISPENLLEAKKLASRTSHLLNSWAYLMKSIQANEVPFDQARDHLFELTLKNRLKEWLLEKVIENRNTKEYDSKGLGVIHLCAVLGYTWSILLFSWANISLDFRDKQGWTALHWAAYYGREKMVAALLSAGARPNLVTDPTKEFLGGCTAADLAQQKGYDGLAAFLAEKCLVAQFKDMQTAGNISGNLETIKAEKSSNPGNANEEEQSLKDTLAAYRTAAEAAARIQGAFREHELKVRSSAVRFASKEEEAKNIIAAMKIQHAFRNFEVRRKIAAAARIQYRFQTWKMRREFLNMRKKAIRIQAAFRGFQVRRQYQKITWSVGVLEKAILRWRLKRKGFRGLQVSQPDEKEGSEAVEDFYKTSQKQAEERLERSVVKVQAMFRSKKAQQDYRRMKLAHEEAQLEYDGMQELDQMATEES

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
154	Phosphorylation	EVHAAPATPGNSYSS EEECCCCCCCCCCCC	30.57	27643528
158	Phosphorylation	APATPGNSYSSSITD CCCCCCCCCCCCCCC	32.10	27643528
159	Phosphorylation	PATPGNSYSSSITDH CCCCCCCCCCCCCCC	19.30	27643528
160	Phosphorylation	ATPGNSYSSSITDHL CCCCCCCCCCCCCCC	19.89	27643528
161	Phosphorylation	TPGNSYSSSITDHLS CCCCCCCCCCCCCCC	19.95	27643528
162	Phosphorylation	PGNSYSSSITDHLSP CCCCCCCCCCCCCCC	24.46	27643528
164	Phosphorylation	NSYSSSITDHLSPKI CCCCCCCCCCCCCCE	21.22	19880383
168	Phosphorylation	SSITDHLSPKIVAED CCCCCCCCCCEEEEE	22.26	19880383
192	Phosphorylation	NTGFEVRSNSLGSRN CCCCEEECCCCCCCC	35.63	23776212
194	Phosphorylation	GFEVRSNSLGSRNHE CCEEECCCCCCCCCE	35.04	23776212
197	Phosphorylation	VRSNSLGSRNHEIRL EECCCCCCCCCEEEE	34.89	23776212
319	Phosphorylation	DALLNNGYGSQDSFG CHHCCCCCCCCCCHH	18.74	30407730
321	Phosphorylation	LLNNGYGSQDSFGRW HCCCCCCCCCCHHHH	23.48	30407730
324	Phosphorylation	NGYGSQDSFGRWVNN CCCCCCCCHHHHHHH	23.20	23111157
694	Phosphorylation	NISGNLETIKAEKSS CCCCCHHHHHHHHCC	30.83	24894044
743	Phosphorylation	EHELKVRSSAVRFAS HHCHHHHHHHHHHCC	26.15	24894044

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CMTA5_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CMTA5_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CMTA5_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of CMTA5_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.