CLRN3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CLRN3_HUMAN
• UniProt AC: Q8NCR9
• Protein Name: Clarin-3
• Gene Name: CLRN3
• Organism: Homo sapiens (Human).
• Sequence Length: 226
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MPTTKKTLMFLSSFFTSLGSFIVICSILGTQAWITSTIAVRDSASNGSIFITYGLFRGESSEELSHGLAEPKKKFAVLEILNNSSQKTLHSVTILFLVLSLITSLLSSGFTFYNSISNPYQTFLGPTGVYTWNGLGASFVFVTMILFVANTQSNQLSEELFQMLYPATTSKGTTHSYGYSFWLILLVILLNIVTVTIIIFYQKARYQRKQEQRKPMEYAPRDGILF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
57	Methylation	FITYGLFRGESSEEL EEEEEEECCCCHHHH	53.68	-
83	N-linked_Glycosylation	AVLEILNNSSQKTLH EHEEHHCCCCCHHHH	39.32	UniProtKB CARBOHYD
131	Phosphorylation	LGPTGVYTWNGLGAS CCCCCEECCCCCCHH	15.28	18452278
218	Phosphorylation	EQRKPMEYAPRDGIL HHCCCCCCCCCCCCC	18.69	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CLRN3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CLRN3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CLRN3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.